tommy [dot] andersson [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
- Interleukin-6 drives melanoma cell motility through p38α-MAPK-dependent up-regulation of WNT5A expression.
- Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.
- WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells
- WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism.
- Cysteinyl leukotriene receptor expression pattern affects migration of breast cancer cells and survival of breast cancer patients.
- Elevated level of wnt5a protein in localized prostate cancer tissue is associated with better outcome.
- Methylation and loss of secreted frizzled-related protein 3 enhances melanoma cell migration and invasion.
- Retracted Manuscript: The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERα negative breast cancer.
- WNT5A Signaling Contributes to A beta-Induced Neuroinflammation and Neurotoxicity
- A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion.
- The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of Eralpha negative breast cancer.
- WNT-5a-CKIalpha signaling promotes beta -catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.
- Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells.
- Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
- Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer.
- TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells
- The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
- beta 2 Integrins target Rap GTPases to the plasma membrane by means of degranulation
- A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
- Dietary supplementation of carbonate promotes spontaneous tumorigenesis in a rat gastric stump model.
- Nitric oxide produced in response to engagement of beta 2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion
- Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
- Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.
- Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.
- Critical role for complement receptor 3 (CD11b/CD18), but not for Fc receptors, in killing of Streptococcus pyogenes by neutrophils in human immune serum.
- E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor
- Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival
- Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.
- Wnt-5a has tumor suppressor activity in thyroid carcinoma
- Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis.
- Engagement of beta2 integrins recruits 14-3-3 proteins to c-Cbl in human neutrophils.
- Streptococcal M5 protein prevents neutrophil phagocytosis by interfering with CD11b/CD18 receptor-mediated association and signaling.
- p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
- p38-MAPK Signals Survival by Phosphorylation of Caspase-8 and Caspase-3 in Human Neutrophils.
- Down-regulation of Rac activity during beta 2 integrin-mediated adhesion of human neutropolis.
- Fgr but not Syk tyrosine kinase is a target for beta2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophils.
- Oxidized low-density lipoprotein induces calpain-dependent cell death and ubiquitination of caspase 3 in HMEC-1 endothelial cells.
- Sphingosine 1-phosphate antagonizes human neutrophil apoptosis via p38 mitogen-activated protein kinase.
- Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion.
- Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas.
- The adhesion receptor CD-31 can be primed to rapidly adjust the neutrophil cytoskeleton.
- p38 Mitogen-activated protein kinase and phosphatidylinositol 3-kinase activities have opposite effects on human neutrophil apoptosis.