Göran Landberg
Titel
Gästprofessor
Organisation
040-331 95 3
Goran [dot] Landberg [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2012
- Automated image analysis of cyclin D1 protein expression in invasive lobular breast carcinoma provides independent prognostic information
- Downregulation of miR-92a Is Associated with Aggressive Breast Cancer Features and Increased Tumour Macrophage Infiltration.
- Low ERK Phosphorylation in Cancer-Associated Fibroblasts Is Associated with Tamoxifen Resistance in Pre-Menopausal Breast Cancer
- Med1 plays a critical role in the development of tamoxifen resistance
- The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ER alpha, and is an independent prognostic factor in node-negative breast cancer
- 2011
- A non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to tamoxifen.
- Cyclin D1, Id1 and EMT in breast cancer
- Food sources of fat and sex hormone receptor status of invasive breast tumors in women of the malmö diet and cancer cohort.
- FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function
- Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche.
- Isolation and characterization of progenitor-like cells from human renal proximal tubules.
- PKA-induced phosphorylation of ER alpha at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer
- Risk of recurrence following delayed large flap reconstruction after mastectomy for breast cancer.
- Stromal Expression of β-Arrestin-1 Predicts Clinical Outcome and Tamoxifen Response in Breast Cancer.
- Tumour-related factors and prognosis in breast cancer detected by screening.
- 2010
- Down-Regulation of the Oncogene Cyclin D1 Increases Migratory Capacity in Breast Cancer and Is Linked to Unfavorable Prognostic Features.
- Genomic alterations in histopathologically normal breast tissue from BRCA1 mutation carriers may be caused by BRCA1 haploinsufficiency.
- Is duration of breastfeeding related to risk of different breast cancer subgroups?
- PKC alpha expression is a marker for breast cancer aggressiveness
- Parity and age at first childbirth in relation to the risk of different breast cancer subgroups
- STROMA-DERIVED MARKERS PREDICTING BREAST CANCER PROGNOSIS AND TREATMENT RESPONSE
- Validation of cytoplasmic-to-nuclear ratio of survivin as an indicator of improved prognosis in breast cancer
- p27(Kip1) is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients.
- p27(Kip1) is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients.
- 2009
- Anthropometric factors in relation to different tumor biological subgroups of postmenopausal breast cancer.
- Cyclin D1 expression is associated with poor prognostic features in estrogen receptor positive breast cancer
- Differential expression of cytoplasmic and stromal beta-arrestin-1 is associated with separate aspects of tumor behavior in breast cancer
- Erythropoietin Receptor Expression and Correlation to Tamoxifen Response and Prognosis in Breast Cancer.
- Estrogen Receptor-{alpha} Phosphorylation at Serine-118 and Tamoxifen Response in Breast Cancer.
- Extranuclear Coactivator Signaling Confers Insensitivity to Tamoxifen.
- Hypoxia, Snail and incomplete epithelial-mesenchymal transition in breast cancer.
- Inactivation of the retinoblastoma tumour suppressor pathway in premenopausal breast cancer is associated with resistance to tamoxifen
- Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer
- JAM-A expression positively correlates with poor prognosis in breast cancer patients
- Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer.
- Parity and age at first childbirth in relation to the risk of different breast cancer subgroups.
- Parity in relation to survival following breast cancer.
- Phosphorylation of the oestrogen receptor alpha at serine 305 and prediction of tamoxifen resistance in breast cancer.
- Role of p27 in tamoxifen response in breast cancer cell lines
- Serum calcium and tumour aggressiveness in breast cancer: a prospective study of 7847 women.
- Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.
- The Bcl-xL inhibitor of apoptosis is preferentially expressed in cutaneous squamous cell carcinoma compared with that in keratoacanthoma.
- WNT-5a-CKIalpha signaling promotes beta -catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.
- 2008
- Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer
- C4b-binding protein in Alzheimer's disease: Binding to Abeta(1-42) and to dead cells.
- C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.
- Cyclin E confers a prognostic value in premenopausal breast cancer patients with tumours exhibiting an infiltrative growth pattern.
- Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study.
- Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer.
- HER2 status in hormone receptor positive premenopausal primary breast cancer adds prognostic, but not tamoxifen treatment predictive, information.
- HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors.
- Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer.
- Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer
- Oestrogen receptor beta immunohistochemistry: time to get it right? Authors' response
- Oestrogen receptors alpha and beta show different associations to clinicopathological parameters and their co-expression might predict a better response to endocrine treatment in breast cancer.
- Plant foods and estrogen receptor {alpha} and {beta} defined breast cancer: observations from the Malmo Diet and Cancer cohort.
- 2007
- Breast tumours following combined hormone replacement therapy express favourable prognostic factors.
- CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer
- Diet and body constitution in relation to sub-groups of breast cancer defined by tumour grade, proliferation and key cell cycle regulators.
- Expression of the cytoskeleton linker protein ezrin in human cancers
- Hypoxia and breast cancer: prognostic and therapeutic implications
- Transcriptional upregulation and unmethylation of the promoter region of p16 in invasive basal cell carcinoma cells and partial co-localization with the gamma2 chain of laminin-332.
- 2006
- Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients.
- Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer
- CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance
- Cyclin A1 expression and associations with disease characteristics in childhood acute lymphoblastic leukemia.
- Cyclin e overexpression reduces infiltrative growth in breast cancer - Yet another link between proliferation control and tumor invasion
- Cyclin e overexpression reduces infiltrative growth in breast cancer: yet another link between proliferation control and tumor invasion.
- High progesterone receptor expression correlates to the effect of adjuvant tamoxifen in premenopausal breast cancer patients.
- Hypoxia inducible factor-1alpha is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response.
- Increased expression of cyclin A1 protein is associated with all-trans retinoic acid-induced apoptosis.
- MTA1, a transcriptional activator of breast cancer amplified sequence 3
- Subcellular localization, modification and protein complex formation of the cdk-inhibitor p16 in Rb-functional and Rb-inactivated tumor cells.
- 2005
- A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.
- Adverse effect of adjuvant tamoxifen in premenopausal breast cancer with cyclin D1 gene amplification.
- C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation.
- Cyclin E overexpression obstructs infiltrative behavior in breast cancer: a novel role reflected in the growth pattern of medullary breast cancers.
- Cyclin I is expressed in human breast cancer and closely associated with VEGF and KDR expression.
- ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis
- ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells.
- Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival
- Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival.
- Expression of cyclin A1 and cell cycle proteins in hematopoietic cells and acute myeloid leukemia and links to patient outcome.
- Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.
- High ID2 protein expression correlates with a favourable prognosis in patients with primary breast cancer and reduces cellular invasiveness of breast cancer cells.
- Hypoxia-induced dedifferentiation of tumor cells - A mechanism behind heterogeneity and aggressiveness of solid tumors.
- Ki67 and p53 immunohistochemistry reduces interobserver variation in assessment of Barrett's oesophagus.
- Microarray-based Analyses of Hypoxia-induced Transcriptional Changes in Breast Cancer Cell Lines
- Pathology parameters and adjuvant tamoxifen response in a randomised premenopausal breast cancer trial.
- Tumor-specific VEGF-A and VEGFR2 in postmenopausal breast cancer patients with long-term follow-up. Implication of a link between VEGF pathway and tamoxifen response.
- Tumor-specific expression of vascular endothelial growth factor receptor 2 but not vascular endothelial growth factor or human epidermal growth factor receptor 2 is associated with impaired response to adjuvant tamoxifen in premenopausal breast cancer.
- 2004
- Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients.
- Erythropoietin enhances response to treatment in patients with advanced breast cancer
- Expression of vascular endothelial growth factor protein in human renal cell carcinoma.
- Overexpression of cyclin E protein is associated with specific mutation types in the p53 gene and poor survival in human breast cancer
- Regulation of the cyclin A1 protein is associated with its differential subcellular localization in hematopoietic and leukemic cells.
- Retinoblastoma protein function and p16(INK4a) expression in actinic keratosis, squamous cell carcinoma in situ and invasive squamous cell carcinoma of the skin and links between p16(INK4a) expression and infiltrative behavior.
- Retinoblastoma protein in human renal cell carcinoma in relation to alterations in G1/S regulatory proteins
- 2003
- C-erbB2, p27 and G1/S aberrations in human primary breast cancer
- Expression of cyclin D1, D3, E, and p27 in human renal cell carcinoma analysed by tissue microarray
- Expression of the leukotriene D4 receptor CysLT1, COX-2, and other cell survival factors in colorectal adenocarcinomas.
- Gene expression profiling of ductal carcinomas in situ and invasive breast tumors
- Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ.
- Invade or Proliferate? Two Contrasting Events in Malignant Behavior Governed by p16(INK4a) and an Intact Rb Pathway Illustrated by a Model System of Basal Cell Carcinoma.
- Lower molecular weight forms of cyclin e: super activators of the cell cycle?
- Regional cyclin D1 overexpression or hypoxia correlate inversely with heterogeneous oestrogen receptor-alpha expression in human breast cancer.
- The RING-H2 protein RNF11 is differentially expressed in breast tumours and interacts with HECT-type E3 ligases
- The breast cancer-associated gene Di12 has oncogenic activity
- Tissue microarray analyses of G1/S-regulatory proteins in ductal carcinoma in situ of the breast indicate that low cyclin D1 is associated with local recurrence.
- Tumor specific VEGF-A and VEGFR2/KDR protein are co-expressed in breast cancer
- 2002
- Cyclin D3 protein content in human renal cell carcinoma in relation to cyclin D1 and clinico-pathological parameters
- Cyclin E and P27 protein content in human renal cell carcinoma: Clinical outcome and associations with cyclin D
- Multiparameter analyses of cell cycle regulatory proteins in human breast cancer: a key to definition of separate pathways in tumorigenesis.
- The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node
