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Christian Winkler

Titel

gästforskare

Organisation

Brain Repair and Imaging in Neural Systems (BRAINS)

Telefon 046-2220527

Mobil +491757002180

E-post Christian [dot] Winkler [at] med [dot] lu [dot] se

Publikationer (hämtat ur Lunds universitets publikationsdatabas)

författare

2012
- Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.
2011
- Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics.
2009
- Impact of grafted serotonin and dopamine neurons on development of L-DOPA-induced dyskinesias in parkinsonian rats is determined by the extent of dopamine neuron degeneration.
2007
- Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
- The functional impact of the intrastriatal dopamine neuron grafts in parkinsonian rats is reduced with advancing disease
2006
- Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats.
- Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia.
2005
- Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy.
- Reversal of dyskinesias in an animal model of Parkinson's disease by continuous L-DOPA delivery using rAAV vectors.
2004
- Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.
2003
- Regulation of neuropeptide mRNA expression in the basal ganglia by intrastriatal and intranigral transplants in the rat Parkinson model.
2002
2001
- Growth and functional efficacy of intrastriatal nigral transplants depend on the extent of nigrostriatal degeneration
2000
- EGF infusion stimulates the proliferation and migration of embryonic progenitor cells transplanted in the adult rat striatum
- Transplantation in the rat model of Parkinson's disease: ectopic versus homotopic graft placement
1997
- Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease

Visa detaljerad publikationslista

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
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