Karl-Erik Andersson
Titel
professor emeritus
Organisation
Karl-Erik [dot] Andersson [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2011
- Cannabinor, a Selective Cannabinoid-2 Receptor Agonist, Improves Bladder Emptying in Rats With Partial Urethral Obstruction.
- Effects of the Gonadotropin-Releasing Hormone Antagonist Ganirelix on Normal Micturition and Prostaglandin E-2-Induced Detrusor Overactivity in Conscious Female Rats
- Exogenously Administered Bombesin and Gastrin Releasing Peptide Contract the Female Rat Urethra In Vivo and In Vitro
- Exogenously Administered Bombesin and Gastrin Releasing Peptide Contract the Female Rat Urethra In Vivo and In Vitro
- Thromboxane A(2) induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms.
- 2010
- Effects of Cannabinor, a Novel Selective Cannabinoid 2 Receptor Agonist, on Bladder Function in Normal Rats.
- Localization and Function of Cannabinoid Receptors in the Corpus Cavernosum: Basis for Modulation of Nitric Oxide Synthase Nerve Activity.
- TRPA1 Receptor Induced Relaxation of the Human Urethra Involves TRPV1 and Cannabinoid Receptor Mediated Signals, and Cyclooxygenase Activation
- The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder
- Transient Receptor Potential A1 and Cannabinoid Receptor Activity in Human Normal and Hyperplastic Prostate: Relation to Nerves and Interstitial Cells.
- 2009
- Distribution and Function of Cannabinoid Receptors 1 and 2 in the Rat, Monkey and Human Bladder
- Receptor-induced phasic activity of newborn mouse bladders is inhibited by protein kinase C and involves T-type Ca channels.
- Signal transduction pathways of muscarinic receptor mediated activation in the newborn and adult mouse urinary bladder.
- Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra-Evidence for a Functional Role for TRPA1 in the Outflow Region.
- Vardenafil-induced relaxation and cyclic nucleotide levels in normal and obstructed rat urinary bladder.
- 2008
- Distribution and Function of the Hydrogen Sulfide-Sensitive TRPA1 Ion Channel in Rat Urinary Bladder
- Melatonin restores impaired contractility in aged guinea pig urinary bladder
- Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo.
- Simultaneous registration of intraabdominal and intravesical pressures during cystometry in conscious rats-Effects of bladder outlet obstruction and intravesical PGE(2).
- 2007
- Dysregulation of cGMP-dependent protein kinase 1 (PKG-1) impairs erectile function in diabetic rats: influence of in vivo gene therapy of PKG1 alpha
- Effect of melatonin on age associated changes in guinea pig bladder function
- Effects of Tolterodine on Afferent Neurotransmission in Normal and Resiniferatoxin Treated Conscious Rats.
- Immunohistochemical Distribution of Cyclic GMP-Dependent Protein Kinase-1 in Human Prostate Tissue.
- Merck fellowships contribute to the continued growth of clinical pharmacology in Sweden
- Phosphodiesterases (PDEs) and PDE inhibitors for treatment of LUTS
- Urodynamic effects of a novel EP(1) receptor antagonist in normal rats and rats with bladder outlet obstruction.
- 2006
- Antimuscarinic drugs in detrusor overactivity and the overactive bladder syndrome: motor or sensory actions?
- Bladder volume alters cholinergic responses of the isolated whole mouse bladder
- Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle.
- Effects of a vitamin D analogue in a rat model of bladder outlet obstruction.
- Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: Immunohistochemical and molecular biology study
- Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate
- Location of interstitial cells and neurotransmitters in the mouse bladder
- Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder
- Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis
- Pharmacokinetic and pharmacodynamic features of dapoxetine, a novel drug for 'on-demand' treatment of premature ejaculation.
- Phasic non-micturition contractions in the bladder of the anaesthetized and awake rat.
- Phosphodiesterase 5 in the female pig and human urethra: morphological and functional aspects.
- Tachykinins: Role in Detrusor Overactivity?
- Treatment-resistant detrusor overactivity - underlying pharmacology and potential mechanisms.
- Update on phosphodiesterase (PDE) isoenzymes as pharmacologic targets in urology: Present and future
- Urodynamic effects of intravesical administration of the new small/intermediate conductance calcium activated potassium channel activator NS309 in freely moving, conscious rats.
- 2005
- A dose-dependent dual effect of oestrogen on voiding in the male mouse?
- ATP- and adenosine-induced relaxation of the smooth muscle of the pig urethra.
- Alpha1 adrenoceptor subtypes and bladder function.
- Cyclic AMP-specific and cyclic GMP-specific phosphodiesterase isoenzymes in human cavernous arteries - immunohistochemical distribution and functional significance
- Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: Relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves
- Effects in vitro and in vivo by apomorphine in the rat corpus cavernosum.
- Human bladder as a novel target for vitamin D receptor ligands
- Nocturia: morbidity and management in adults
- Recent advances in understanding the biology of diabetes-associated bladder complications and novel therapy
- The role of corticotropin releasing factor and its antagonist, astressin, on micturition in the rat
- 2004
- Activation of dopamine D-4 receptors by ABT-724 induces penile erection in rats
- Antimuscarinics for treatment of overactive bladder
- Antimuscarinics for treatment of overactive bladder.
- Cystometric findings in mice lacking muscarinic M2 or M3 receptors
- Detrusor contraction - Focus on muscarinic receptors
- Detrusor responses to prostaglandin E2 and bladder outlet obstruction in wild-type and Ep1 receptor knockout mice.
- Female pig urethral tone is dependent on Rho guanosine triphosphatases and Rho-associated kinase.
- Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone
- Mechanisms of Disease: central nervous system involvement in overactive bladder syndrome.
- New pharmacologic targets for the treatment of the overactive bladder: an update.
- Pharmacology of the lower urinary tract: basis for current and future treatments of urinary incontinence.
- Protective effect of an oral endothelin converting enzyme inhibitor on rat detrusor function after outlet obstruction.
- Summary of the recommendations on sexual dysfunctions in men
- The role of the rhabdosphincter in female rat voiding
- Transmitters contributing to the voiding contraction in female rats.
- Urinary bladder contraction and relaxation: Physiology and pathophysiology
- Urodynamic effects of the K+ channel (KCNQ) opener retigabine in freely moving, conscious rats.
- Veränderungen der Muskarinrezeptoren der alternden Harnblase Changes in muscarinic receptors of the aging bladder
- 2003
- A review of the physiology and pharmacology of peripheral (vaginal and clitoral) female genital arousal in the animal model - Discussion
- Actions of tramadol on micturition in awake, freely moving rats.
- Antimuscarinics and the overactive detrusor-which is the main mechanism of action?
- Bladder overactivity in mice after 1 week of outlet obstruction. Mainly afferent dysfunction?
- CNS involvement in overactive bladder: pathophysiology and opportunities for pharmacological intervention.
- Desmopressin in elderly patients with nocturia: short-term safety and effects on urine output, sleep and voiding patterns.
- Differences between nocturics and non-nocturics in voiding patterns: an analysis of frequency-volume charts from community-dwelling elderly.
- Effects of resiniferatoxin desensitization of capsaicin-sensitive afferents on detrusor over-activity induced by intravesical capsaicin, acetic acid or ATP in conscious rats
- Effects of tramadol on rat detrusor overactivity induced by experimental cerebral infarction.
- Ejaculatory dysfunction: why all alpha-blockers are not equal.
- Erectile physiological and pathophysiological pathways involved in erectile dysfunction.
- Estrogen receptor subtypes and afferent signaling in the bladder.
- Expression of nitric oxide synthase immunoreactivity in the human female intramural striated urethral sphincter
- Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo.
- Introduction
- Morphology phenotype and ultrastructure of fibroblastic cells from normal and neuropathic human detrusor: Absence of myofibroblast characteristics
- Nerve-mediated bladder contraction is impaired by cytokines: involvement of inducible nitric oxide synthase.
- Nocturia and associated morbidity in a community-dwelling elderly population.
- Partial outlet obstruction enhances modular autonomous activity in the isolated rat bladder
- Storage and voiding symptoms: pathophysiologic aspects.
- Summary.
- Third International Conference on the Management of Erectile Dysfunction: Linking pathophysiology and therapeutic response
- Tramadol inhibits rat detrusor overactivity caused by dopamine receptor stimulation.
- Vasculogenic erectile dysfunction: Newer therapeutic strategies - Discussion
- 2002
- Actions of the new antimuscarinic compound Lu 25-109 on isolated human and pig detrusor.
- Alpha-adrenoceptors and benign prostatic hyperplasia: basic principles for treatment with alpha-adrenoceptor antagonists.
- Bladder activation: afferent mechanisms.
- Carbon monoxide relaxes the female pig urethra as effectively as nitric oxide in the presence of YC-1.
- Effects of NAD-299, a new, highly selective 5-HT(1A) receptor antagonist, on bladder function in rats.
- Effects of beta(3)-adrenoceptor stimulation on prostaglandin E-2-induced bladder hyperactivity and on the cardiovascular system in conscious rats
- Effects of gamma-aminobutyrate B receptor modulation on normal micturition and oxyhemoglobin induced detrusor overactivity in female rats.
- Effects of selective beta 2 and beta 3-adrenoceptor agonists on detrusor hyperreflexia in conscious cerebral infarcted rats
- Effects of tiagabine, a gamma-aminobutyric acid re-uptake inhibitor, on normal rat bladder function.
- Enhancement of apomorphine-induced penile erection in the rat by a selective alpha(1D)-adrenoceptor antagonist.
- Expression of nitric oxide synthase in bladder smooth muscle cells: Regulation by cytokines and L-arginine
- Future drugs for the treatment of benign prostatic hyperplasia.
- Intravesical adenosine triphosphate stimulates the micturition reflex in awake, freely moving rats.
- Morphological and functional characterization of a rat vaginal smooth muscle sphincter
- New directions for erectile dysfunction therapies.
- Nitric oxide independent activation of guanylate cyclase by YC-1 causes erectile responses in the rat.
- Overactive bladder--pharmacological aspects.
- Overview consensus statement
- Pharmacologic perspective on the physiology of the lower urinary tract.
- Potential benefits of muscarinic M-3 receptor selectivity
- Role of supraspinal alpha 1-adrenoceptors for voiding in conscious rats with and without bladder outlet obstruction
- Tamsulosin: an overview
- The pharmacological treatment of nocturia
- Treatment of the overactive bladder: possible central nervous system drug targets.
- What is nocturnal polyuria?
- alpha-Melanocyte stimulating hormone and oxytocin induced penile erections, and intracavernous pressure increases in the rat
- alpha-Melanocyte stimulating hormone and oxytocin induced penile erections, and intracavernous pressure increases in the rat.
- 1998
- 1997
- Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and lower oesophagogastric junction
- NANC transmitters in the female pig urethra--localization and modulation of release via alpha 2-adrenoceptors and potassium channels
- Neurotransmitter release evoked by alpha-latrotoxin in the smooth muscle of the female pig urethra
- Regionala kurser rekryterar doktorander. Stort intresse for fortsatt forskning
- 1995
- 1992
- 1990
- Effects of alpha-adrenoceptor active drugs, prostaglandin F2 alpha and vasopressin on cystic and hepatic arteries of pig and man
- Effects of isradipine, a new calcium antagonist, on maternal cardiovascular system and uterine activity in labour
- Maternal and fetal cardiovascular changes after intravenous injections of isradipine to pregnant women
