Carl Borrebaeck
Titel
Vicerektor, professor
046-2229613
+46708218330
Carl [dot] Borrebaeck [at] rektor [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2012
- Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties.
- Expanded clinical and experimental use of SOX11-using a monoclonal antibody
- Quantitative proteomics targeting classes of motif-containing peptides using immunoaffinity-based mass spectrometry.
- Synergistic augmentation of CD40-mediated activation of antigen-presenting cells by amphiphilic poly(γ-glutamic acid) nanoparticles.
- The GARD assay for assessment of chemical skin sensitizers.
- Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?
- 2011
- A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
- Design of recombinant antibody microarrays for membrane protein profiling of cell lysates and tissue extracts.
- Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells.
- Knock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo
- Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases.
- Pattern rules: biomarker signatures for sensitization as an alternative to animal testing.
- Proteomic analysis and discovery using affinity proteomics and mass spectrometry.
- Recombinant antibodies for the generation of antibody arrays.
- Surrogate antigens as targets for proteome-wide binder selection
- The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation
- 2010
- A community standard format for the representation of protein affinity reagents
- Distribution, cellular localization, and therapeutic potential of the tumor-associated antigen Ku70/80 in glioblastoma multiforme.
- Fc epsilon RI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis
- Identification of uniquely expressed transcription factors in highly purified B-cell lymphoma samples.
- Immunomodulatory nanoparticles as adjuvants and allergen-delivery system to human dendritic cells: Implications for specific immunotherapy.
- Minimum information about a protein affinity reagent (MIAPAR)
- Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients
- SOX11 expression correlates to promoter methylatuion and regulates tumor growth in hematopoietic malignancies
- Tissue proteome profiling of preeclamptic placenta using recombinant antibody microarrays
- Two-step in vitro antibody affinity maturation enables estradiol-17β assays with more than 10-fold higher sensitivity.
- 2009
- Antibody-based microarrays.
- Attovial-based antibody nanoarrays.
- CD4+ T-cells have a key instructive role in educating dendritic cells in allergy
- Design of high-density antibody microarrays for disease proteomics: Key technological issues.
- Identification of molecular targets associated with transformed diffuse large B cell lymphoma using highly purified tumor cells.
- Implementing affinity proteomics into the clinic - diagnosis and prediction of metastatic breast cancer
- Proteome Survey Using Affinity Proteomics and Mass Spectrometry
- SOX11 but not SOX4 is a prognostic marker for improved recurrence free survival in epithelial ovarian cancer
- Safe cosmetics without animal testing? Contributions of the EU Project Sens-it-iv
- Strategy for surveying the proteome using affinity proteomics and mass spectrometry.
- Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt's lymphoma.
- The transcription factor Sox11 is a prognostic factor for improved recurrence-free survival in epithelial ovarian cancer
- 2008
- Affinity-based protein chips: Diagnostic applications in oncology
- Antibody microarray-based proteomics: High-throughput application
- Antibody microarray-based screening: Label-dependent vs Label-free detection - that is the question
- Augmented Phl p 5-specific Th2 response after exposure of Dendritic Cells to allergen in complex with specific IgE compared to IgG1 and IgG4
- Design of recombinant antibody microarrays for cell surface membrane proteomics
- Detection of pancreatic cancer using antibody microarray-based serum protein profiling
- Functionally associated targets in mantle cell lymphoma as defined by DNA microarrays and RNA interference
- Histamine receptors on human dendritic cells influence the Th2 response in grass pollen allergy
- Histamine receptors on human dendritic cells influence the Th2 response in grass pollen allergy
- Identification of a strongly activating human anti-CD40 antibody that suppresses HIV-1 infection
- Light-induced immobilization of biomolecules as an attractive alternative to micro-droplet dispensing-based arraying technologies
- Multiplexed Lipid Dip-Pen Nanolithography on Subcellular Scales for the Templating of Functional Proteins and Cell Culture
- Nanoparticles as allergen-delivery system and their effect on human dendritic cells
- Nuclear expression of the Non-B Cell Lineage Sox11 Transcription Factor Identifies Mantle Cell Lymphoma
- Phenotypic protein profiling of different B cell sub-populations using antibody CD-microarrays
- Plasma Protein Biomarker Signatures As Indicators Of The Effects Of Immuno Gene Tumor Therapy In Patients With Glioblastoma Multiforme
- Recombinant antibody microarrays as a tool to decipher complex disease associated protein signatures
- Screening of Inflammatory Markers in Preeclampsia Using Antibody Microarrays
- Sensitivity of HIV-1 primary isolates to human anti-CD40 antibody-mediated suppression is related to co-receptor use
- Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays.
- Sox11, a non-B cell lineage transcription factor, is overexpressed in mantle cell lymphoma
- Transcriptional profiling of human skin-resident Langerhans cells and CD1a+ dermal dendritic cells: differential activation states suggest distinct functions.
- Transformed diffuse large B cell lymphomas differ from follicular lymphomas in both gene and protein expression
- antibody microarray analysis of directly labelled proteomes
- γ-PGA nanoparticles as allergen-delivery system and their effect on human dendritic cells
- 2007
- Antibody Microarray-based Proteomics
- Antibody microarray based oncoproteomics - analysis of breast cancer proteomes
- Antibody microarray-based serum protein profiling of system lupus erythematosus and systemic sclerosis
- Antibody microarray-based serum protein profiling of systemic lupus erythematosus and systemic sclerosis
- Antibody technology in Clinical Oncology
- Antibody-based microarrays: from focused assays to proteome-scale analysis
- Applications of antibody microarrays in oncoproteomics
- Augmented phlp5-specific Th2 response after exposure of DCs with allergen-specific IgE, compared to specific IgG1 or IgG4.
- Cross-talk between dendritic cells and memory T-cells induces specific activity in atopic patients
- Cross-talk between dendritic cells and memory T-cells induces specific activity in atopic patients
- Deciphering disease specific biomarker signatures using recombinant antibody microarrays
- Design of atto-vial based recombinant antibody arrays combined with a planar wave-guide detection system
- Design of recombinant antibody microarrays for complex proteome analysis: Choice of sample labeling-tag and solid support
- Design of recombinant antibody microarrays for serum protein profiling: Targeting of complement proteins
- Design of self-addressabl antibody microarrays based on recombinant scFv antibodies microarray adapted by molecular design
- Detection and prediction of disease progression using affinity proteomics
- Detection of cancer using affinity proteomics based on antibody microarrays
- Development of atto-vial based antibody arrays
- Developmentof atto-vial based antibody arrays
- Developmentof atto-vial based antibody arrays
- Differential serum protein profiling of GBM patients immunized with autologous glioma-cells transfected with INF-gamma gene, and their controls
- High-throughput proteomics using antibody microarrays: an update
- Identification of disease specific serum biomarkers using recombinant antibody microarrays and directly labelled proteomes
- Improved diagnosis and therapy for mantle cell lymphomas
- Membrane protein profiling using recombinant antibody microarrays
- Parallel gene expression profiling of mantle cell lymphoma - How do we transform 'omics data into clinical practice
- Predictors in Clinical Oncology
- Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays
- Progress in miniaturization of protein arrays - a step closer to high-density nanoarrays
- ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome
- Quantitative interpretation of gold nanoparticle-based bioassays designed for detection of immunocomplex formation
- Recombinant antibdy microarray based oncoproteomics detects cancer and defines a predictor of survival for pancreatic carcinoma
- Recombinant antibody microarrays – Focussed and global approaches for high-through proteomics
- Serum protein profiling of metastatic breast cancer
- Specific IgE facilitates antigen presentation by dendritic cells and augments an allergic Th2 response
- The regulatory role of Dendritic Cells in Allergic Immune responses
- Transcriptional profiling of 17 human dendritic cell populations and models – defining the cellular source for an in vitro test system for sensitizing compounds
- Transcriptional profiling of 17 human dendritic cell populations and models – defining the cellular source for an in vitro test system for sensitizing compounds
- Translational oncoproteomics based on recombinant antibody microarrays
- 2006
- Antibody microarray based oncoproteomics
- Antibody microarray based oncoproteomics - State-of-the-Art Lecture
- Antibody microarray based oncoproteomics - analysis of breast cancer proteomes
- Antibody microarray-based oncoproteomics
- Antibody microarrays: Current status and key technological advances
- Antibody microarrays: technology and analysis if serum proteomes from cancer patients
- Antibody miroarray based oncoproteomics – technology and clinical applications
- Antibodymicroarray based oncoproteomics – technology and clinical applications
- Assessment of frequency and functional properties of DC subsets in peripheral blood from healthy and allergic individuals
- Biomarker discovery to development
- Cancer proteomics
- Cross talk between T cells and dendritic cells induce specific transcriptional activity in atopic patients
- Cross talk between T cells and dendritic cells induce specific transcriptional activity in atopic patients
- Design of recombinant antibodies for high-throughput proteomics
- Escherichia coli TolA tolerates multiple amino-acid substitutions as revealed by screening randomized variants for membrane integrity and phage receptor function
- From gene expression analysis to tissue microarrays - A rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies
- Functional and transcriptional profiling of MUTZ-3, a myeloid cell line acting as a model for dendritic cells
- Genomics and proteomics in the diagnosis, prognosis and treatment of cancer
- High-throughput cancer proteomics using antibody-based microarrays
- High-throughput cancer proteomics using recombnant antibody microarrays - a novel approach for biomarker discovery and diagnostics
- High-throughput membrane proteomics using recombinant antibody microarrays
- Identification of protein expression signatures associated with Helicobacter pylori infection and gastric adenocarcinoma using recombinant antibody microarrays
- Improved affinity coupling for antibody microarrays: Engineering of double-(His)(6)-tagged single framework recombinant antibody fragments
- Interactions between dendritic cells and epithelial cells in allergic disease
- Mantle cell lymphomas acquire increased expression of CCL4, CCL5 and 4-1BB-L implicated in cell survival
- Membrane protein profling on antibody-based microarrays: a novel approach for cancer diagnostics and biomarker discovery
- One-step fractionation of complex proteomes enables detection of low abundant analytes using antibody-based microarrays
- Protein expression profiling in normal and malignant stomach tissue using recombinant antibody microarrays
- Protein expression profiling using recombinant antibody microarrays
- Rapid induction of apoptosis in B-cell lymphoma by functionally isolated human antibodies
- Recombinant antibody microarrays; key technological issues
- Serum protein profiling of pancreatic cancer using human recombinant antibody microarrays
- The human CD77(-) B cell population represents a heterogeneous subset of cells comprising centroblasts, centrocytes, and plasmablasts, prompting phenotypical revision
- The human IgE-encoding transcriptome to assess antibody repertoires and repertoire evolution
- The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis
- Will proteomics deliver useful tools for the clinician?
- 2005
- Antibody microarrays for cancer proteome profiling
- Antibody microarrays: Technology and analysis of serum proteomes from cancer patients
- Biocompatability of surfaces for antibody microarrays: Design of macroporous silicon substrates
- Biocompatibility of surfaces for antibody microarrays: design of macroporous silicon substrates
- Cancer proteomics
- Dendritic cells as predictors of allergenicity
- From gene expression to tissue microarray - a rational approach to target identification
- Functional and transcriptional profiling of MUTZ-3 . A myeloid cell line acting as a model for dendritic cells
- Gene family clustering identifies functionally associated subsets of human in vivo blood and tonsillar dendritic cells
- Genome-wide comparison of phage M13-infected vs. uninfected Escherichia coli
- Genomic and functional delineation of dendritic cells and memory T cells derived from grass pollen-allergic patients and healthy individuals.
- Gravimetric antigen detection utilizing antibody-modified lipid bilayers
- High expression of cyclin B1 predicts a favorable outcome in patients with follicular lymphoma
- Individuals with occupational allergy to detergent enzymes display a differential transcriptional regulation and cellular immune response
- Microarrays based on affinity-tagged SCFV antibodies: Sensitive detection of analyte in complex proteomes
- Microarrays based on affinity-tagged single-chain Fv antibodies: Sensitive detection of analyte in complex proteomes
- Nanosphere induced gene expression in human dendritic cells
- Protein expression profiling in normal and malignant stomach tissue using recombinant antibody microarrays
- Transcriptional profiling and assessment of cell lines as in vitro models for mantle cell lymphoma
- Will proteomics/genomics change our ways to diagnose and predict cancer
- 2004
- A novel mammalian display system for the selection of protein-protein interactions by decoy receptor engagement
- Biocampatability of surfaces for antibody microarrays: design of macroporous silicon substrates
- CD27(-) CD4(+) memory T cells define a differentiated memory population at both the functional and transcriptional levels
- Design of antibody microarrays for high-throughput proteomics
- Design of antibody microarrays for high-throughput proteomics
- Designing therapeutic antibodies
- High-density microarray analysis in cancer and allergy
- High-throughput proteomics on antibody-based microarrays: the importance of probe and surface design
- High-throughput proteomics using antibody microarrays
- Human reconstituted lung epithelium as a tool for in vitro immunotoxicity screening
- Increased expression of Ki-67 in mantle cell lymphoma is associated with de-regulation of several cell cycle regulatory components, as identified by global gene expression analysis
- Mega-dense nanoarrays: the challenge of novel antibody microarray formats
- Microarrays based on affinity-tagged scFv antibodies: sensitive detection of analytes in complex proteomes
- Microarrays based on affinity-tagged scFv antibodies: sensitive detection of analytes in complex proteomes
- Molecular mechanisms involved in atopic versus nonatopic response to grass pollen
- Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics
- Protein microarrays for high-throughput proteomics
- Protein-protein interaction studies using protein chip technology by mass spectrometry
- Proteome analysis based on human recombinant antibody microarrays
- Proteome analysis based on human recombinant antibody microarrays
- Understanding the biology of lymphomas using transcriptional profiling
- 2003
- Affinity and Epitope Profiling of Mouse Anti-CD40 Monoclonal Antibodies
- Antibody microarray in proteome analysis: A drug discovery tool?
- Antibody microarrays – developing a tool for high-throughput proteomics
- CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays
- Designing proteins to crystallize through beta-strand pairing
- Expression of CD137 (4-1BB) on Human Follicular Dendritic Cells
- Functional profiling and transcriptional differences between the CD4+ memory populations CD27+ and CD27-.
- Gene expression profiling of mantle cell lymphonas
- Germinal Centers Regulate Human Th2 Development1
- Internalising human anti-tumor antibodies.
- Patterns of DNA-labeled and scFv-antibody-carrying lipid vesicles directed by material-specific Immobilization of DNA and supported lipid bilayer formation on an Au/SiO2 template
- Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of mouse B cells from anti-immunoglobulin M-induced apoptosis
- Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of naïve B-cells from anti-IgM induced apoptosis
- Probe and surface design for antibody microarrays
- Protein microarrays based on affinity-tagged scFv antibodies: sensitive detection of analyte
- Protein-microarray developments
- Recombinant antibody microarrays - a viable option?
- The effect of recombinant allergenic enzymes on dendritic cells derived from atopic and non-atopic individuals and their effect on autologous effector memory T cells.
- The mechanism of bacterial infection by filamentous phages involves molecular interactions between TolA and phage protein 3 domains
- Transcriptional profiling of mantle cell lymphomas
- 2002
- Antibody Microarrays in Proteomics – Pros and Cons
- Antibody evolution beyond nature
- Antibody evolution from the centre to the periphery: applied to a human antibody fragment recognising the tumour-associated antigen mucin-1.
- Antibody-mediated neutralization of cytomegalovirus: modulation of efficacy induced through the IgG constant region.
- Characterization of specific IgE response in vitro against protein and drug allergens using atopic and normal donors
- DNA microarray analysis in cancer target discovery
- Germinal center B cells constitute a predominant physiological source of IL-4: Implication for Th2 development in vivo
- Global reprogramming of dendritic cells in response to a concerted action of inflammatory mediators
- High-density microarray analysis for genome wide screening in biomedicin
- High-throughput genomics
- High-throughput proteomics: Protein arrays - Introduction
- Mantle cell lymphomas express a distinct genetic signature affecting lymphocyte trafficking and growth regulation as compared with subpopulations of normal human B cells.
- Modulation of the CD40-CD40 ligand interaction using human anti-CD40 single-chain antibody fragments obtained from the n-CoDeR phage display library
- Nanostructured high surface area supports for high sensitivity protein chips
- Selective infection of E. coli as a function of a specific molecular interaction.
- SinFab.s as designer probes for a protein microarrays
- Single framework antibody fragments - designed for protein chip applications
- Single framework antibody fragments designed for protein array applications
- Single framework antibody fragments for protein microarrays
- Single framework recombinant antibody fragments designed for protein chip applications
- 2001
- A central core structure in an antibody variable domain determines antigen specificity
- CD40 employs p38 MAP kinase in IgE isotype switching
- Gene expression analysis of monocyte-derived dendritic cells
- Protein chips based on recombinant antibody fragments: A highly sensitive approach as detected by mass spectrometry
- The immune diversity in a test tube - Non-immunised antibody libraries and functional variability in defined protein scaffolds
- 1996
- 1994
- 1991
- 1989
