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Publikationer (hämtat ur Lunds universitets publikationsdatabas)
- A Central Role for GRB10 in Regulation of Islet Function in Man.
- Exceptional evolutionary divergence of human muscle and brain metabolomes parallels human cognitive and physical uniqueness.
- Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity
- Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a six months exercise intervention.
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
- Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms.
- TCF7L2 is a master regulator of insulin production and processing.
- A common variant upstream of the PAX6 gene influences islet function in man.
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
- First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle.
- Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.
- Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
- Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
- Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.
- The Triglyceride Content in Skeletal Muscle Is Associated with Hepatic But Not Peripheral Insulin Resistance in Elderly Twins.
- Relation between cycling exercise capacity, fiber-type composition, and lower extremity muscle strength and muscle endurance.
- Running with regulation
- The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.
- A mRNA marker for glycolytic muscle fibres may be used to determine fibre type composition in human skeletal muscle
- Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes.
- Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes.
- Resistance to exercise-induced changes in the global DNA methylation pattern of skeletal muscle in individuals with a family history of type 2 diabetes
- TCF7L2-conferred apoptosis in pancreatic beta cells involves the p53 pathway
- Evaluation of chloride channel-3 as a potential target for TCF7L2-dependent impairment of insulin secretion
- Hormone-sensitive lipase (HSL) is also a retinyl ester hydrolase: evidence from mice lacking HSL.
- The impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
- Tissue-specific alternative splicing of TCF7L2
- Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.
- Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle.
- Attainment of brown adipocyte features in white adipocytes of hormone-sensitive lipase null mice.
- Effect of exercise on gene transcript profiles in skeletal muscle of individuals with and without a family history of diabetes
- Hormone-sensitive lipase is necessary for normal mobilization of lipids during sub-maximal exercise.
- Proteomic studies in animal models of diabetes