Johan Flygare
Titel
Forskarassistent
Organisation
046-222 06 87
Johan [dot] Flygare [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2012
- 2011
- 2010
- 2008
- Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.
- RPS19 Deficiency Leads to Reduced Proliferation and Increased Apoptosis but Does Not Affect Terminal Erythroid Differentiation in a Cell Line Model of Diamond-Blackfan Anemia
- 2007
- Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation
- Diamond-Blackfan anemia: erythropoiesis lost in translation.
- Endoglin is not Critical for Hematopoietic Stem Cell Engraftment and Reconstitution, but Regulates Adult Erythroid Development.
- Endoglin is not critical for hematopoietic stem cell engraftment and reconstitution but regulates adult erythroid development
- Human RPS19, the gene mutated in Diamond Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits.
- IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
- 2006
- 2005
- Deficiency of ribosomal protein S19 in CD34+ cells generated by siRNA blocks erythroid development and mimics defects seen in Diamond-Blackfan anemia.
- Development of cellular models for ribosomal protein S19 (RPS19)-deficient diamond-blackfan anemia using inducible expression of siRNA against RPS19.
- 2003
- Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.
- Proliferation deficiency of multipotent hematopoietic progenitors in ribosomal protein S19 (RPS19)-deficient Diamond-Blackfan anemia improves following RPS19 gene transfer
