Håkan Olsson

författare

• 2013
  • A variant in FTO shows association with melanoma risk not due to BMI
  • Establishing a Southern Swedish Malignant Melanoma OMICS and Biobank Clinical Capability
  • Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability.
  • Prognostic factors in lung cancer in a defined geographical area over two decades with a special emphasis on gender.
• 2012
  • A Nonsynonymous Polymorphism in IRS1 Modifies Risk of Developing Breast and Ovarian Cancers in BRCA1 and Ovarian Cancer in BRCA2 Mutation Carriers
  • A prospective, population-based study of 40000 women regarding host factors, UV exposure and sunbed use in relation to risk and anatomic site of cutaneous melanoma.
  • Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer
  • Breast cancer and spider telangiectasias at diagnosis and its relation to histopathology and prognosis: a population-based study.
  • Cancer among patients with diabetes, obesity and abnormal blood lipids: a population-based register study in Sweden.
  • Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.
  • Distribution of aldehyde dehydrogenase 1-positive stem cells in benign mammary tissue from women with and without breast cancer.
  • Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker
  • Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
  • Increased incidence of childhood, prostate and breast cancers in relatives of childhood cancer patients.
  • Measures of birth size in relation to risk of prostate cancer: the Malmo Diet and Cancer Study, Sweden
  • Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies
  • Metal-on-metal joint bearings and hematopoetic malignancy A review
  • Molecular profiling reveals low- and high-grade forms of primary melanoma
  • Ovarian Cancer and Body Size: Individual Participant Meta-Analysis Including 25,157 Women with Ovarian Cancer from 47 Epidemiological Studies
  • Ovarian cancer and smoking: individual participant meta-analysis including 28 114 women with ovarian cancer from 51 epidemiological studies
  • Perceptions of genetic research and testing among members of families with an increased risk of malignant melanoma
  • Prevalence of germline TP53 mutations and history of Li-Fraumeni syndrome in families with childhood adrenocortical tumors, choroid plexus tumors, and rhabdomyosarcoma: A population-based survey.
  • Sickness absence among cancer patients in the pre-diagnostic and the post-diagnostic phases of five common forms of cancer.
  • The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
• 2011
  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
  • Androgen receptor htSNPs in relation to androgen levels and OC use in young women from high-risk breast cancer families.
  • Breast cancer patients with lobular cancer more commonly have a father than a mother diagnosed with cancer
  • Experiences of living with advanced colorectal cancer from two perspectives - Inside and outside.
  • Food sources of fat and sex hormone receptor status of invasive breast tumors in women of the malmö diet and cancer cohort.
  • Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients.
  • Genetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers.
  • Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3
  • Genome-wide association study identifies three new melanoma susceptibility loci
  • High-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer
  • IGF1 htSNPs in relation to IGF-1 levels in young women from high-risk breast cancer families: implications for early-onset breast cancer
  • IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.
  • Increased cancer risks among arthroplasty patients: 30year follow-up of the Swedish Knee Arthroplasty Register.
  • Molecular serum portraits in patients with primary breast cancer predict the development of distant metastases.
• 2010
  • Analysis of protein expression in pure cell nuclei populations isolated from human breast cancer tissue by DNA flow cytometric sorting.
  • Are active sun exposure habits related to lowering risk of type 2 diabetes mellitus in women, a prospective cohort study?
  • Association of MC1R Variants and Host Phenotypes With Melanoma Risk in CDKN2A Mutation Carriers: A GenoMEL Study.
  • Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
  • Can a phenotype for recessive inheritance in breast cancer be defined?
  • Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers
  • Genomic alterations in histopathologically normal breast tissue from BRCA1 mutation carriers may be caused by BRCA1 haploinsufficiency.
  • Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
  • Hormonal risk factors in breast cancer in relation to histopathology: a clue to tissue of origin of the tumor?
  • Interactions between oral contraceptive status and GSTM1 and GSTT1 deletions on insulin-like growth factor-1 (IGF-1) plasma levels in young healthy women.
  • Is lobular breast cancer mainly inherited from the father?
  • Is the health of the spouse affected by tumour disease in the wife or husband? A part of population based register studies of cancer in Southern Health Care Region in Sweden
  • Low Cancer Rates among Patients with Dementia in a Population-Based Register Study in Sweden.
  • Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
  • Multiple metastases from cutaneous malignant melanoma patients may display heterogeneous genomic and epigenomic patterns.
  • Occupational exposure to pesticides and bile tract carcinoma in men: results from a European multicenter case-control study
  • Plasma Folate Concentrations Are Positively Associated with Risk of Estrogen Receptor {beta} Negative Breast Cancer in a Swedish Nested Case Control Study.
  • Problems in assessing multiple cutaneous melanoma. A review on the accuracy of a population based cancer registry.
  • Sick leave of spouses to cancer patients before and after diagnosis.
  • Swedish CDKN2A mutation carriers do not present the atypical mole syndrome phenotype.
  • To live with advanced colorectal cancer - life situation for the ill person and the partner
• 2009
  • A pooled analysis of Melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes
  • A population-based cohort study on the use of hormone treatment and endometrial cancer in southern Sweden.
  • Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study.
  • Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis
  • Expression of Helix pomatia Lectin Binding Glycoproteins in Women with Breast Cancer in Relationship to Their Mood Group Phenotypes
  • Folate intake, methylenetetrahydrofolate reductase polymorphisms, and breast cancer risk in women from the Malmö Diet and Cancer cohort.
  • Genome-wide association study identifies three loci associated with melanoma risk
  • Increased breast cancer risk at high plasma folate concentrations among women with the MTHFR 677T allele.
  • Increased mortality in prostate carcinoma and smoking-related disease after parietal cell vagotomy: A long-term follow-up study
  • Influence on the Health of the Partner Affected by Tumor Disease in the Wife or Husband Based on a Population-Based Register Study of Cancer in Sweden.
  • Prediabetes is associated with similar risks during pregnancy and delivery as obesity and overweight
  • Reproductive and Hormonal Factors, and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Results from the International BRCA1/2 Carrier Cohort Study
  • Risk factors of breast cancer in relation to classical histopathology
  • Selection criteria for genetic assessment of patients with familial melanoma
  • Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls
  • The relationship between lifestyle factors and venous thromboembolism among women: a report from the MISS study.
• 2008
  • Aesthetic outcome, patient satisfaction, and health-related quality of life in women at high risk undergoing prophylactic mastectomy and immediate breast reconstruction.
  • Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer.
  • Common sequence variants on 20q11.22 confer melanoma susceptibility
  • Confirmed cancer trends in families of patients with multiple cancers including cutaneous melanoma.
  • Do both heterocyclic amines and omega-6 polyunsaturated fatty acids contribute to the incidence of breast cancer in postmenopausal women of the Malmö diet and cancer cohort?
  • Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study.
  • Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.
  • Lower breast cancer survival in mothers of children with a malignancy: a national study.
  • Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23 257 women with ovarian cancer and 87 303 controls
  • Plant foods and estrogen receptor {alpha} and {beta} defined breast cancer: observations from the Malmo Diet and Cancer cohort.
  • Pregnancies in prediabetic women
  • Prolactin levels, breast-feeding and milk production in a cohort of young healthy women from high-risk breast cancer families: implications for breast cancer risk.
  • Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays.
  • The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions
• 2007
  • A prospective study on dietary fat and incidence of prostate cancer (Malmö, Sweden).
  • Absence of the common IGF1 19 CA-repeat allele is more common among BRCA1 mutation carriers than among non-carriers from BRCA1 families.
  • Antibody microarray based oncoproteomics - analysis of breast cancer proteomes
  • CYP17 genotype is associated with short menstrual cycles, early oral contraceptive use and BRCA mutation status in young healthy women
  • Discussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers
  • Genetic variant of the human homologous recombination-asociated gene RM11 (S¤%%N) impacts the risk of AML/MDS and malignant melanoma
  • High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmo Diet and Cancer cohort
  • In-Source Decay Causes Artifacts in SELDI-TOF MS Spectra.
  • Occupational exposure to endocrine-disrupting compounds and biliary tract cancer among men
  • Occupational exposure to endocrine-disrupting compounds and biliary tract cancer among men
  • Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study: A report from EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group
  • Regression analysis and modelling of data acquisition for SELDI-TOF mass spectrometry.
  • Risk factors for extrahepatic biliary tract carcinoma in men: medical conditions and lifestyle: results from a European multicentre case-control study
  • Serum protein profiling of metastatic breast cancer
  • Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
  • Time to diagnosis, of melanoma: same trend in different continents
• 2006
  • Antibody microarray based oncoproteomics - analysis of breast cancer proteomes
  • Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors
  • Differences in IGFBP-3 regulation between young healthy women from BRCAX families and those belonging to BRCA1/2 families.
  • Increased risk of malignancies in a population-based study of 818 soft-tissue sarcoma patients.
  • Insulin-like growth factor-1 genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating insulin-like growth factor-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families.
  • Occupational factors and risk of adult bone sarcomas: A multicentric case-control study in Europe
  • Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update
• 2005
  • Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
  • Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies
  • Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization.
  • Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers
  • Fat from different foods show diverging relations with breast cancer risk in postmenopausal women.
  • High follicular phase luteinizing hormone levels in young healthy BRCA1 mutation carriers: Implications for breast and ovarian cancer risk.
  • Impact of teenage oral contraceptive use in a population-based series of early-onset breast cancer cases who have undergone BRCA mutation testing
  • Insulin-like growth factor-1 (IGF1) genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating IGF-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families.
  • Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32.
  • Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas
• 2004
  • A familial syndromic association between cutaneous malignant melanoma and neural system tumours: reply from authors
  • Alcohol drinking may increase risk of breast cancer in men: a European population-based case-control study
  • An updated review of the epidemiology of soft tissue sarcoma
  • Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83?000 women with breast cancer from 16 countries
  • Breast cancer and abortions
  • Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
  • Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables
  • Diagnosis and prognosis of breast and ovarian cancer - A population-based study of 234 women
  • Evidence-Based Medicine in the medical curriculum – a guideline
  • Familial risk of tumors associated with hereditary non-polyposis colorectal cancer: a Swedish population-based study.
  • High fat and alcohol intakes are risk factors of postmenopausal breast cancer: A prospective study from the Malmö diet and cancer cohort.
  • Intakes of plant foods, fibre and fat and risk of breast cancer - a prospective study in the Malmö Diet and Cancer cohort.
  • Melanoma and nonmelanoma skin cancer in patients with multiple tumours-evidence for new syndromes in a population-based study.
  • No relations between breast cancer risk and fatty acids of erythrocyte membranes in postmenopausal women of the Malmo Diet Cancer cohort (Sweden)
  • Occupational exposures and non-Hodgkin's lymphoma in Southern Sweden.
  • One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: results of a prospective study in Southern Sweden.
  • The need for oncogenetic counselling - Ten years' experience of a regional oncogenetic clinic
• 2003
  • A prospective study of adiposity and postmenopausal breast cancer risk: The Malmö diet and cancer study.
  • Are smoking-associated cancers prevented or postponed in women using hormone replacement therapy?
  • Author reply.
  • Cancer incidence in relatives of a population-based set of cases of early-onset breast cancer with a known BRCA1 and BRCA2 mutation status
  • Characterization of a Novel Breast Carcinoma Xenograft and Cell Line Derived from a BRCA1 Germ-Line Mutation Carrier.
  • Comparative cytogenetic and DNA flow cytometric analysis of 242 primary breast carcinomas
  • Defective mismatch-repair in patients with multiple primary tumours including colorectal cancer.
  • Differential prognostic impact of the cyclins E and B in premenopausal and postmenopausal women with lymph node-negative breast cancer
  • Expression of cyclins E, A, and B, and prognosis in lymph node-negative breast cancer
  • High proteinase 3-anti-neutrophil cytoplasmic antibody (ANCA) level measured by the capture enzyme-linked immunosorbent assay method is associated with decreased patient survival in ANCA-associated vasculitis with renal involvement
  • Hormone replacement therapy containing progestins and given continuously increases breast carcinoma risk in Sweden.
  • Molecular classification of familial non-BRCA1/BRCA2 breast cancer
  • Relation between the rate of tumour cell proliferation and latency time in radiation associated breast cancer.
  • Risk of ovarian cancer in breast-cancer patients with a family history of either
  • What can we learn from the Million Women Study.
  • Worse survival in breast cancer among women with recent childbirth: results from a Swedish population-based register study.
• 2002
  • A cohort study of reproductive factors and family history of breast cancer in southern Sweden.
  • Alcohol, tobacco and breast cancer - collaborative reanalysis of individual data from 53 epidemiological studies, including 58515 women with breast cancer and 95067 women without the disease
  • Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50 302 women with breast cancer and 96 973 women without the disease
  • Cancer Incidence in BRCA1 mutation carriers
  • Clinical and histopathological features of malignant melanoma in germline CDKN2A mutation families
  • Genetic testing for melanoma
  • High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum
  • Hormone replacement therapy use in relation to tumor biology and breast cancer prognosis
  • Male gynecomastia and risk for malignant tumours - a cohort study
  • Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
  • Postmenopausal breast cancer is associated with high intakes of omega6 fatty acids (Sweden).
  • Variation in BRCA1 cancer risks by mutation position
• 2001
  • Concurrent overexpression of p53 and c-erbB-2 correlates with accelerated cycling and concomitant poor prognosis in node-negative breast cancer
  • Family history of breast and ovarian cancers and BRCA1 and BRCA2 mutations in a population-based series of early-onset breast cancer
  • Functional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families
  • Gender and time differences in initial location and histological grade of non-Hodgkin's lymphomas in Southern Sweden
  • Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families
  • Malignancies during follow-up in an epidemiologically defined systemic lupus erythematosus inception cohort in southern Sweden
  • Prognostic factors in invasive cutaneous malignant melanoma: a population-based study and review
  • RESPONSE: Re: High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
• 2000
  • Estrogen receptor content in malignant breast tumors in men--a review.
  • MYB oncogene amplification in hereditary BRCA1 breast cancer
  • Prognosis and clinical presentation of BRCA2-associated breast cancer
  • Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus
• 1999
  • Correlation between p53, c-erbB-2, and topoisomerase II alpha expression, DNA ploidy, hormonal receptor status and proliferation in 356 node-negative breast carcinomas: prognostic implications
  • Hormone replacement therapy before breast cancer diagnosis significantly reduces the overall death rate compared with never-use among 984 breast cancer patients
  • Immunologic proliferation marker Ki-S2 as prognostic indicator for lymph node-negative breast cancer
  • Incidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutation carriers
  • Reproductive factors in hereditary breast cancer
  • Somatic genetic alterations in BRCA2-associated and sporadic male breast cancer
  • hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden
• 1998
  • Analysis of Swedish male breast cancer family data: a simple way to incorporate a common sibling effect
  • BRCA1-positive patients are small for gestational age compared with their unaffected relatives
  • BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease
  • Do BRCA1 mutations affect the ability to breast feed? Significantly shorter length of breast feeding among BRCA1 mutation carriers compared with their unaffected relatives.
  • Insulin-like growth factor-1 in relation to adult weight and birth weight in healthy nulliparous women
  • Pregnancy-associated breast cancer in BRCA1 and BRCA2 germline mutation carriers
  • Steroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes
• 1997
  • Breast size in relation to endogenous hormone levels, body constitution, and oral contraceptive use in healthy nulligravid women aged 19-25 years
  • Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer
  • Reduced testosterone, 17 beta-oestradiol and sexual hormone binding globulin, and increased insulin-like growth factor-1 concentrations, in healthy nulligravid women aged 19-25 years who were first and/or second degree relatives to breast cancer patients
  • Tumor Biological Features of BRCA1-Induced Breast Cancer
• 1996
  • Chromosome aberrations in prophylactic mastectomies from women belonging to breast cancer families
  • Detection of Germline BRCA1 Mutations in Breast Cancer Patients by Quantitative Messenger RNA in situ Hybridization
  • Founding BRCA1 Mutations in Hereditary Breast and Ovarian Cancer in Southern Sweden
  • Urokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay
• 1995
  • Recurrence-free survival in breast cancer improved by adjuvant tamoxifen--especially for progesterone receptor positive tumors with a high proliferation
  • Temporary increase of FSH levels in healthy, nulliparous, young women after cessation of low-dose oral contraceptive use
• 1994
  • Cathepsin D, both a prognostic factor and a predictive factor for the effect of adjuvant tamoxifen in breast cancer. South Sweden Breast Cancer Group
  • ERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer
  • High frequency of allelic imbalance at the BRCA1 region on chromosome 17q in both familial and sporadic ductal carcinomas
  • Suppression of plasma insulin-like growth factor-1 levels in healthy, nulliparous, young women using low dose oral contraceptives
• 1992
  • Flow cytometric DNA index and S-phase fraction in breast cancer in relation to other prognostic variables and to clinical outcome
  • Image cytometric DNA analysis in human breast cancer analysis may add prognostic information in diploid cases with low S-phase fraction by flow cytometry
  • One or multiple samplings for flow cytometric DNA analyses in breast cancer-prognostic implications?
  • c-myc amplification is an independent prognostic factor in postmenopausal breast cancer
• 1991
  • ERBB2 amplification in breast cancer with a high rate of proliferation
  • Proliferation and DNA ploidy in malignant breast tumors in relation to early oral contraceptive use and early abortions
• 1990
  • Flow cytometry in primary breast cancer: improving the prognostic value of the fraction of cells in the S-phase by optimal categorisation of cut-off levels
  • Indicators of prognosis in node-negative breast cancer