Jia-Yi Li
Titel
professor, forskargruppschef
Organisation
046-2220525
046-2220634
Jia-Yi [dot] Li [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2012
- Axonopathy in Huntington's disease.
- Beyond α-synuclein transfer: pathology propagation in Parkinson's disease.
- Late onset vascular dysfunction in the R6/1 model of Huntington's disease.
- Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient-Derived Induced Pluripotent Stem Cells
- 2011
- IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.
- Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells.
- Neurogenesis In The R6/2 Mouse Model Of Huntington'S Disease Is Impaired At The Level Of Neurod1
- Signs of Degeneration in 12-22-Year Old Grafts of Mesencephalic Dopamine Neurons in Patients with Parkinson's Disease
- alpha-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- 2010
- A simple method for large-scale generation of dopamine neurons from human embryonic stem cells.
- Are synucleinopathies prion-like disorders?
- Characterization of Lewy Body Pathology in 12-and 16-Year Old Intrastriatal Mesencephalic Grafts Surviving in a Patient with Parkinson's Disease
- Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease.
- Foxa2 and Nurr1 Synergistically Yield A9 Nigral Dopamine Neurons Exhibiting Improved Differentiation, Function, and Cell Survival
- GABAergic Differentiation Induced by Mash1 Is Compromised by the bHLH Proteins Neurogenin2, NeuroD1, and NeuroD2.
- 2009
- Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment
- Divalent metal transporter 1 is involved in amyloid precursor protein processing and A{beta} generation.
- Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis.
- Mutant huntingtin interacts with {beta}-tubulin and disrupts vesicular transport and insulin secretion.
- Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis.
- 2008
- Critical issues of clinical human embryonic stem cell therapy for brain repair.
- Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, MSX1, Ngn2, and Pitx3.
- From bench to bed: the potential of stem cells for the treatment of Parkinson's disease
- Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20.
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
- Research in motion: the enigma of Parkinson's disease pathology spread.
- 2007
- "NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells.
- Adult neurogenesis in neurodegenerative diseases
- Axonal transport of neuropeptides: Retrograde tracing study in live cell cultures of rat sympathetic cervical ganglia.
- Fibroblast growth factor-20 increases the yield of midbrain dopaminergic neurons derived from human embryonic stem cells.
- Restorative cell therapy for Parkinson's disease: A quest for the perfect cell
- 2006
- Cholinergic neuronal defect without cell loss in Huntington's disease.
- Failure of transdifferentiation of adult hematopoietic stem cells into neurons.
- Laminin {alpha}1 chain improves laminin {alpha}2 chain deficient peripheral neuropathy.
- Neuropeptide Y-2 receptors are involved in enhanced neurogenic vasoconstriction in spontaneously hypertensive rats
- Transplantation in Parkinson's disease: The future looks bright.
- Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: Effect of in vitro differentiation on graft survival and teratoma formation
- 2005
- Depletion of rabphilin 3A in a transgenic mouse model (R6/1) of Huntington's disease, a possible culprit in synaptic dysfunction.
- Orexin loss in Huntington's disease.
- Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice.
- Stem cell-based therapy for Parkinson's disease.
- Stromal cell-derived inducing activity does not promote dopaminergic differentiation, but enhances differentiation and proliferation of neural stem cell-derived astrocytes.
- Synaptic dysfunction in Huntington's disease: a new perspective
- The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient {beta}-cell mass and exocytosis.
- The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
- 2004
- 2003
- 2002
