Christer Owman
Titel
professor emeritus
Organisation
046-222 05 71
Christer [dot] Owman [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2009
- Deletion of the G protein-coupled Receptor GPR30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-stimulated Insulin Release in Female Mice.
- Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates.
- 2006
- Characterization of the human chemerin receptor - ChemR23/CMKLR1 - as co-receptor for human and simian immunodeficiency virus infection, and identification of virus-binding receptor domains.
- Lysophosphatidic Acid Binds to and Activates GPR92, a G Protein-Coupled Receptor Highly Expressed in Gastrointestinal Lymphocytes
- Residues from transmembrane helices 3 and 5 participate in leukotriene B-4 binding to BLT1
- 2005
- CCR5 N-terminal region plays a critical role in HIV-1 inhibition by Toxoplasma gondii-derived cyclophilin-18
- Fluorescent leukotriene B-4: potential applications
- Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion.
- Non-specific effects of leukotriene synthesis inhibitors on HeLa cell physiology
- Pro- and anti-inflammatory substances modulate expression of the leukotriene B4 receptor, BLT1, in human monocytes.
- The mouse chemerin receptor gene, mcmklr1, utilizes alternative promoters for transcription and is regulated by all-trans retinoic acid
- 2004
- Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype.
- Developments toward a Microfluidic System for Long-Term Monitoring of Dynamic Cellular Events in Immobilized Human Cells.
- Exploring the pharmacology of the leukotriene B-4 receptor BLT1, without the confounding effects of BLT2
- Fatty acid receptors
- Genomic organization and promoter analysis of the gene encoding the mouse chemoattractant-like receptor, CMKLR1.
- 2003
- A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs.
- Differential inhibition of receptor activation by two mouse monoclonal antibodies specific for the human leukotriene B(4) receptor, BLT(1).
- Flow cytometric mapping of the leukotriene B4 receptor, BLT1, in human bone marrow and peripheral blood using specific monoclonal antibodies.
- HIV biological variability unveiled: frequent isolations and chimeric receptors reveal unprecedented variation of coreceptor use.
- Identification of a free fatty acid receptor, FFA(2)R, expressed on leukocytes and activated by short-chain fatty acids.
- Mechanisms of leukotriene B-4-triggered monocyte adhesion
- Molecular mapping of epitopes for interaction of HIV-1 as well as natural ligands with the chemokine receptors, CCR5 and CXCR4.
- Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase.
- Progress in methodology improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors.
- 2002
- 2001
- 2000
- Cloning and characterization of cDNA encoding a novel human leukotriene B(4) receptor
- Cloning of a novel chemoattractant receptor activated by leukotriene B4 and used by human immunodeficiency virus type 1 to infect CD4-positive immune cells. A therapeutic connection to asthma?
- First-generation monoclonal antibodies identifying the human leukotriene B(4) receptor-1
- Genomic organization of the leukotriene B(4) receptor locus of human chromosome 14
- Modulation of (35)SGTPgammaS binding to chinese hamster ovary cell membranes by D(2(short)) dopamine receptors
- 1999
- Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors
- Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors
- Serotonergic agonists behave as partial agonists at the dopamine D2 receptor
- 1998
- Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells
- Molecular mapping of epitopes involved in ligand activation of the human receptor for the neuropeptide, VIP, based on hybrids with the human secretin receptor
- The leukotriene B4 receptor functions as a novel type of coreceptor mediating entry of primary HIV-1 isolates into CD4-positive cells
- 1997
- Leukotriene B4 is the functional ligand binding to and activating the cloned chemoattractant receptor, CMKRL1
- Method for identifying ligands activating either excitatory or inhibitory G-protein-coupled receptors by functional coexpression in Xenopus oocytes
- Molecular cloning and tissue distribution of cDNA encoding a novel chemoattractant-like receptor
- Vascular effects of proteinase-activated receptor 2 agonist peptide
- 1996
- Cloning of cDNA encoding a putative chemoattractant receptor
- Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues
- Neonatal chronic sympathectomy in normotensive rats affects pial arteries: enhanced stiffness and reduced capacity to dilate
- Neonatal pre-ganglionic sympathectomy affects morphometrically defined architecture in rat cerebral arteries
- 1994
- A morphometric study of the effect of bilateral cervical sympathetic ganglionectomy on the architecture of pial arteries in spontaneously hypertensive and normotensive rats
- An in vivo study of the effect of 5-HT and sympathetic nerves on transferrin and transthyretin mRNA expression in rat choroid plexus and meninges
- Dynorphin B is present in sensory and parasympathetic nerves innervating pial arteries
- 1993
- 1992
- Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging
- Effects of vasoactive intestinal polypeptide on choroid plexus blood flow and cerebrospinal fluid production
- Inhibition of cerebrospinal fluid formation by omeprazole
- Neuroendocrine regulatory mechanisms in the choroid plexus-cerebrospinal fluid system
- Vasoactive intestinal polypeptide and acetylcholine coexist with neuropeptide Y, dopamine-beta-hydroxylase, tyrosine hydroxylase, substance P or calcitonin gene-related peptide in neuronal subpopulations in cranial parasympathetic ganglia of rat
- 1991
- An amplifying effect of exogenous and neurally stored 5-hydroxytryptamine on the neurogenic contraction in rat tail artery
- Epithelial cells purified from choroid plexus have receptors for vasoactive intestinal polypeptide
- Relaxation of the human uterine artery by atrial natriuretic peptide is independent of the endothelium
- Simultaneous and continuous measurement of choroid plexus blood flow and cerebrospinal fluid production: effects of vasoactive intestinal polypeptide
- The influence of neuropeptide Y and norepinephrine on ovulation in the rat ovary
- 1990
- Actions of sex steroids and corticosteroids on rabbit choroid plexus as shown by changes in transport capacity and rate of cerebrospinal fluid formation
- Adrenoceptors mediating contraction in the human uterine artery
- Central origins of preganglionic fibers to the sphenopalatine ganglion in the rat. A fluorescent retrograde tracer study with special reference to its relation to central catecholaminergic systems
- Cooling enhances alpha 2-adrenoceptor-mediated vasoconstriction in human hand veins
- Distribution of peptidergic nerves in the choroid plexus, focusing on coexistence of neuropeptide Y, vasoactive intestinal polypeptide and peptide histidine isoleucine
- Effect on cortical blood flow of electrical stimulation of trigeminal cerebrovascular nerve fibres in the rat
- Effects of oophorectomy, sympathetic denervation and sex steroids on uterine norepinephrine content and myometrial contractile response to norepinephrine in the guinea pig
- Further evidence for a prejunctional action of neuropeptide Y on cholinergic motor neurons in the rat uterine cervix
- Histaminergic effects on the isolated rat ovarian artery during the estrous cycle
- Immunocytochemical demonstration of contractile cells in the human ovarian follicle
- Kinetic studies on uptake of serotonin and noradrenaline into pial arteries of rats
- Neuropeptide Y co-exists with vasoactive intestinal polypeptide and acetylcholine in parasympathetic cerebrovascular nerves originating in the sphenopalatine, otic, and internal carotid ganglia of the rat
- Origins and pathways of choline acetyltransferase-positive parasympathetic nerve fibers to cerebral vessels in rat
- Peptidergic vasodilator nerves in the peripheral circulation and in the vascular beds of the heart and brain
- Selective electrical stimulation of postganglionic cerebrovascular parasympathetic nerve fibers originating from the sphenopalatine ganglion enhances cortical blood flow in the rat
- The neuropeptides vasoactive intestinal polypeptide, peptide histidine isoleucine and neuropeptide Y modulate 3Hnoradrenaline release from sympathetic nerves in the choroid plexus
- Ultrastructural cerebrovascular changes in a model of subarachnoid hemorrhage in baboon based on triple cisternal blood injection
- Vasoactive intestinal polypeptide in the PMSG-primed immature rat ovary and its effect on ovulation in the isolated rat ovary perfused in vitro
- 1989
- Cerebrovascular serotonergic receptors mediating vasoconstriction: further evidence for the existence of 5-HT2 receptors in rat and 5-HT1-like receptors in guinea-pig basilar arteries
- Changes in transport functions of isolated rabbit choroid plexus under the influence of oestrogen and progesterone
- Characterization of dilatation induced by electrical field stimulation in mammalian cerebral and peripheral vessels
- Characterization of the contractile and dilatory responses to electrical field stimulation in guinea-pig and monkey isolated pial arteries
- Chronic nicotine treatment eliminates asymmetry in striatal glucose utilization following unilateral transection of the mesostriatal dopamine pathway in rats
- Corticosteroid action on choroid plexus: reduction in Na+-K+-ATPase activity, choline transport capacity, and rate of CSF formation
- Endothelin is a potent constrictor of human intracranial arteries and veins
- Galanin-positive nerves of trigeminal origin innervate rat cerebral vessels
- Myometrial norepinephrine in human pregnancy. Elevated levels in various disorders leading to cesarean section
- Origins and pathways of cerebrovascular nerves storing substance P and calcitonin gene-related peptide in rat
- Origins of substance P- and calcitonin gene-related peptide-containing nerves in the internal carotid artery of rat
- Prejunctional alpha 2-adrenoreceptors modulate the stimulated release of noradrenaline in isolated follicle strips from bovine ovaries
- Protective effects of chronic nicotine treatment on lesioned nigrostriatal dopamine neurons in the male rat
- Serotonin potentiates noradrenaline-induced vasoconstriction through 5-HT1-type receptors in guinea pig basilar artery
- Serotonin uptake into cerebrovascular nerve fibers of rat, visualization by immunohistochemistry, disappearance following sympathectomy, and release during electrical stimulation
- Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist
- Trigeminal fibre collaterals storing substance P and calcitonin gene-related peptide associate with ganglion cells containing choline acetyltransferase and vasoactive intestinal polypeptide in the sphenopalatine ganglion of the rat. An axon reflex modulating parasympathetic ganglionic activity?
- 1988
- A heterogeneous population of alpha 1-adrenoceptors mediates contraction of the isolated follicle wall from the bovine ovary
- Cellular localization of ovarian histamine, its cyclic variations, and histaminergic effects on ovulation in the rat ovary perfused in vitro
- Immunocytochemical localization of galanin in the rat male and female genital tracts and motor effects in vitro
- On the presence of serotonin in cerebrovascular sympathetic nerves and the interaction with noradrenaline at specific receptors mediating vasoconstriction
- Origins and pathways of cerebrovascular vasoactive intestinal polypeptide-positive nerves in rat
- Vasoconstrictor effects in spinal cord of the substance P antagonist D-Arg, D-Trp7,9 Leu11-substance P (Spantide) and somatostatin and interaction with thyrotropin releasing hormone
