Dorthe Grabau
Titel
överläkare, dr med vet
Organisation
046-173511
Dorthe [dot] Grabau [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2013
- Completion axillary dissection can safely be omitted in screen detected breast cancer patients with micrometastases. A decade's experience from a single institution.
- Targeting HMG-CoA reductase with statins in a window-of-opportunity breast cancer trial.
- The combination of Ki67, histological grade and estrogen receptor status identifies a low-risk group among 1,854 chemo-naïve women with N0/N1 primary breast cancer.
- 2012
- Biphasic, Hyperdiploid Breast Tumors in Children: A Distinct Entity?
- Breast cancer. Quality Assurance and Prognosis.
- Comparison of the oestrogen and progesterone receptor status in primary breast carcinomas as evaluated by immunohistochemistry and immunocytochemistry: a consecutive series of 267 patients.
- Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.
- Increased gene copy number of KIT and VEGFR2 at 4q12 in primary breast cancer is related to an aggressive phenotype and impaired prognosis.
- The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
- The role of AIB1 and PAX2 in primary breast cancer: validation of AIB1 as a negative prognostic factor.
- 2011
- Analysis of sentinel node biopsy - a single-institution experience supporting the use of serial sectioning and immunohistochemistry for detection of micrometastases by comparing four different histopathological laboratory protocols.
- CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers.
- Distinction of isolated tumour cells and micrometastasis in lymph nodes of breast cancer patients according to the new Tumour Node Metastasis (TNM) definitions
- Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies
- Value of post-operative reassessment of estrogen receptor alpha expression following neoadjuvant chemotherapy with or without gefitinib for estrogen receptor negative breast cancer
- 2010
- AIB1 is a predictive factor for tamoxifen response in premenopausal women.
- Determination of HER2 amplification in primary breast cancer using dual-colour chromogenic in situ hybridization is comparable to fluorescence in situ hybridization: a European multicentre study involving 168 specimens
- Evidence for tissue factor phosphorylation and its correlation with protease activated receptor expression and the prognosis of primary breast cancer.
- High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
- Identification of Subtypes in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Reveals a Gene Signature Prognostic of Outcome.
- Ki-67 as a long-term prognostic factor in lobular breast cancer
- Ki67 proliferation as a biomarker in neo-adjuvant breast cancer studies - core biopsy versus surgical sample
- The prognostic value of Ki67 is dependent on estrogen receptor status and histological grade in premenopausal patients with node-negative breast cancer.
- Three different antibodies for estrogen receptor analysis in breast cancer - implications for positive frequency, reproducibility and clinical outcome
- Tissue factor phosphorylation requires protease activated receptor-2 expression: Correlation with the prognosis of human breast cancer
- 2009
- Experiences from treatment-predictive KRAS testing; high mutation frequency in rectal cancers from females and concurrent mutations in the same tumor.
- Is the prognostic value of Ki-67 dependent on ER status and histological grade?
- Significantly higher expression of vascular endothelial growth factor (VEGF) and shorter survival after recurrences in premenopausal node negative patients with triple negative breast cancer
- 2008
- Breast cancer patients with micrometastases only: Is a basis provided for tailored treatment?
- Different routine histopathology after frozen section of sentinel nodes in breast cancer
- Epidermal Growth Factor Receptor (EGFR) in primary breast cancer-protein expression, but not gene copy number, gives important prognostic information in tamoxifen treated patients
- Epidermal growth factor receptor (EGFR) and the estrogen receptor modulator amplified in breast cancer (AIB1) for predicting clinical outcome after adjuvant tamoxifen in breast cancer.
- The CD44(+)/CD24(-) phenotype is enriched in basal-like breast tumors
- Tiling array-CGH for the assessment of genomic similarities among synchronous unilateral and bilateral invasive breast cancer tumor pairs.
