Thomas Hellmark
Titel
Forskare, PhD, Docent
Organisation
046-2220701
+46709425085
Thomas [dot] Hellmark [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2012
- Citrate treatment reduces endothelial death and inflammation under hyperglycaemic conditions.
- Decreased Neutrophil Apoptosis in Quiescent ANCA-Associated Systemic Vasculitis.
- Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.
- Galectin-8 in IgA Nephritis: Decreased Binding of IgA by Galectin-8 Affinity Chromatography and Associated Increased Binding in Non-IgA Serum Glycoproteins.
- Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis.
- 2011
- Circulating NET remnants in ANCA-AASV
- Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitis.
- Comparison of characteristics of natural autoantibodies to MPO and anti-MPO autoantibodies from patients with MPA
- Pseudomonas aeruginosa in cystic fibrosis: Pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.
- 2010
- Autoimmune kidney diseases.
- Biomedicinsk utbildning vid Medicinska fakulteten, Lunds universitet. Utbildning och arbetsliv – en alumnundersökning
- Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression.
- Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis.
- Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals
- Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes
- 2009
- Natural autoantibodies against myeloperoxidase, protease 3 and glomerular basement membrane in normal healthy individuals
- Neutrophil degranulation and complement release in ANCA-associated vasculitis: an in vitro study
- Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin
- Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.
- Studies of mechanisms underlying the prolonged neutrophil survival in ANCA-associated systemic vasculitis
- 2008
- 2007
- A 59-kd renal antigen as a new target for rapidly progressive glomerulonephritis
- Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with Goodpasture disease with or without anti-neutrophil cytoplasmic antibodies
- Natural anti-GBM antibodies from normal human sera recognize alpha 3(IV)NC1 restrictively and recognize the same epitopes as anti-GBM antibodies from patients with anti-GBM disease
- PR3 and CD177 are co-expressed on neutrophil plasma membranes in patients with ANCA associated systemic vasculitis
- Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils.
- Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes
- 2006
- A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis
- Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.
- Integrin alpha 3 beta 1, a Novel Receptor for alpha 3(IV) noncollagenous domain and a trans-dominant inhibitor for integrin alpha v beta 3
- Mapping of myeloperoxidase epitopes recognized by MPO-ANCA using human-mouse MPO chimers
- 2005
- 2004
- Epitope mapping of anti-PR3 antibodies using chimeric human/mouse PR3 recombinant proteins.
- Patients with Goodpasture's disease have two normal COL4A3 alleles encoding the NC1 domain of the type IV collagen {alpha}3 chain.
- The - 564 A/G polymorphism in the promoter region of the proteinase 3 gene associated with Wegener's granulomatosis does not increase the promoter activity.
- 2003
- Immunodominant epitopes of alpha3(IV)NC1 induce autoimmune glomerulonephritis in rats.
- Point mutations of single amino acids abolish ability of alpha(3) NC1 domain to elicit experimental autoimmune glomerulonephritis in rats
- The prognostic significance in Goodpasture's disease of specificity, titre and affinity of anti-glomerular-basement-membrane antibodies.
- 2002
- 2000
- 1999
- 1997
- Anti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope
- Autoantibodies against components of renal basement membrane
- Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?
- Characterization of the processing and granular targeting of human proteinase 3 after transfection to the rat RBL or the murine 32D leukemic cell lines
- Comparison of anti-GBM antibodies in sera with or without ANCA
- 1996
- 1994
