Thomas Laurell
Titel
Professor
046-2227540
Thomas [dot] Laurell [at] elmat [dot] lth [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2013
- A Critical Evaluation of Inflammatory Markers in Huntington’s Disease Plasma
- A simple one-step assay platform based on fluorescence quenching of macroporous silicon
- Chromosome 19 Annotations with Disease Speciation - A First Report from the Global Research Consortium
- Establishing a Southern Swedish Malignant Melanoma OMICS and Biobank Clinical Capability
- Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability.
- 2012
- Acoustic Trapping
- Acoustic radiation- and streaming-induced microparticle velocities determined by microparticle image velocimetry in an ultrasound symmetry plane
- Acoustic trapping with seed-particles for submicron particle enrichment.
- Acoustofluidics 11: Affinity specific extraction and sample decomplexing using continuous flow acoustophoresis.
- Acoustofluidics 5: Building microfluidic acoustic resonators.
- Lab on a chip: Scandinavia
- Label-free somatic cell cytometry in raw milk using acoustophoresis.
- Miniaturized and Automated High-Throughput Verification of Proteins in the ISET Platform with MALDI MS.
- Molecular microheterogeneity of prostate specific antigen in seminal fluid by mass spectrometry.
- Optimizing nanovial outlet designs for improved solid-phase extraction in the integrated selective enrichment target-ISET.
- Porous silicon antibody microarrays for quantitative analysis: Measurement of free and total PSA in clinical plasma samples.
- Seed particle-enabled acoustic trapping of bacteria and nanoparticles in continuous flow systems.
- Sol-Gel Derived Nanoporous Compositions for Entrapping Small Molecules and Their Outlook toward Aptamer Screening
- Standardization and Utilization of Biobank Resources in Clinical Protein Sciene with Examples of Emerging Applications
- Two-hundredfold volume concentration of dilute cell and particle suspensions using chip integrated multistage acoustophoresis.
- 2011
- Automated and temperature-controlled micro-PIV measurements enabling long-term-stable microchannel acoustophoresis characterization.
- Biogrid-a microfluidic device for large-scale enzyme-free dissociation of stem cell aggregates.
- Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples
- Drug Localization in Different Lung Cancer Phenotypes by MALDI Mass Spectrometry Imaging
- Efficient removal of platelets from peripheral blood progenitor cell products using a novel micro-chip based acoustophoretic platform.
- Emerging clinical applications of microchip-based acoustophoresis.
- Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process
- Forthcoming Lab on a Chip tutorial series on acoustofluidics: Acoustofluidics-exploiting ultrasonic standing wave forces and acoustic streaming in microfluidic systems for cell and particle manipulation
- Improving flow cytometric assay performance using in-line acoustophoretic washing of lysed blood samples
- MRM assay for quantitation of complement components in human blood plasma - a feasibility study on multiple sclerosis.
- Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels
- Noncovalent antibody immobilization on porous silicon combined with miniaturized Solid-Phase Extraction (SPE) for array based immunoMALDI assays
- Synthesis of NaYF4 : Yb^{3+}/Er^{3+} upconverting nanocrystals in a capillary-based continuous microfluidic reaction system
- 2010
- Acoustophoretic Separation of Yeast Cells
- Acoustophoretic pretreatment of cell lysate prior to FACS analysis
- Aptamer microarray mediated capture and mass spectrometry identification of biomarker in serum samples.
- Bioelectrochemical studies of azurin and laccase confined in three-dimensional chips based on gold-modified nano-/microstructured silicon
- Cell separation based on acoustophoresis and applications in health care
- Characterization of PSA in clinical samples by mass spectrometry
- Characterization of PSA in clinical samples by mass spectrometry
- Clinical proteomics; protein expression research within disease - a challenging task
- Continuous separation of cells and particles in microfluidic systems
- Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry
- Identification of prostate specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms
- Isotope labeled internal standards (ILIS) as a basis for quality control in clinical studies using plasma samples
- MRM assay for quantification of complement components in human blood plasma
- MRM assay for quantification of complement components in human blood plasma
- Mass spectrometric strategy for clearcut identification of prostate specific antigen in clinical Samples
- Measuring the local pressure amplitude in microchannel acoustophoresis
- Multiple sclerosis: Identification and clinical evaluation of novel CSF biomarkers
- Non-contact acoustic cell trapping in disposable glass capillaries.
- 2009
- Acoustic Whole Blood Plasmapheresis Chip for Prostate Specific Antigen Microarray Diagnostics.
- Acoustic differential extraction for forensic analysis of sexual assault evidence.
- Acoustic whole blood plasmaphersis for PSA microarray diagnostics
- An analytical platform for clinical blood sample studies
- Blood plasma peptide profiling by equalizing and multiplex complementary SPE using the microfluidic ISET platform
- Buffer medium exchange in continuous cell and particle streams using ultrasonic standing wave focusing
- Compound tissue imaging signal output generated by different matrix deposition platforms
- Decomplexing biofluids using microchip based acoustophoresis
- Harmonic microchip acoustophoresis: a route to online raw milk sample precondition in protein and lipid content quality control
- Identification of novel candidate protein biomarkers for the post-polio syndrome — Implications for diagnosis, neurodegeneration and neuroinflammation
- Isotope labeled internal standards (ILIS) as the basis for QC-Control in human plasma analysis
- Multiple sclerosis: identification and clinical evaluation of Novel CSF biomarkers for diagnosis and monitoring of disease progression and therapeutic effect
- Multiplex approach for identification of PSA variants in clinical samples
- On-chip microfluidic systems for determination of L-glutamate based on enzymatic recycling of substrate
- Review of cell and particle trapping in microfluidic systems.
- The Signal Intensity in Imaging MALDI-MS Is Dependent on Matrix Deposition
- 2008
- Acoustic microfluidic chip technology to facilitate automation of phage display selection
- Acoustic resonances in straight micro channels: Beyond the 1D-approximation
- Acoustophoresis in wet-etched glass chips
- Acoustophoresis in wet-etched glass chips
- Alteration of prostate specific antigen (PSA) in blood linked to cancer
- Decomplexing biofluids using microchip based acoustophoresis
- ENSAM: Europium Nanoparticles for Signal Enhancement of Antibody Microarrays on Nanoporous Silicon.
- Implementation of a Protein Profiling Platform Developed as an Academic-Pharmaceutical Industry Collaborative Effort
- On chip affinity selection of antibodies using ultrasonic standing waves
- Stability study on human plasma – controlling clinical sample quality
- 2007
- Acoustic Differential Extraction - ultrasonic DNA-extraction from sexual assault evidence
- Chip integrated strategies for acoustic separation and manipulation of cells and particles
- Containerless reaction monitoring in ionic liquids by means of Raman microspectroscopy
- Fluorescent Activated Cell Sorter using Ultrasound Standing Waves in Micro Channels
- Free flow acoustophoresis: Microfluidic-based mode of particle and cell separation
- Implementation of a protein profiling platform developed as an academic-pharmaceutical industry collaborative effort
- Improved ultrasonic micro array separation using far field ultrasonic excitation
- Noninvasive acoustic cell trapping in a microfluidic perfusion system for online bioassays
- On-chip affinity selection of antibodies using ultrasonic standing waves.
- Plasmapheresis in microfluidic channels using acoustic standing waves
- Polymeric integrated selective enrichment target (ISET) for solid-phase-based sample preparation in MALDI-TOF MS
- Porous Silicon Protein Microarray Technology and Ultra-/ superhydrophobic States for Improved Bioanalytical Readout
- Porous silicon surfaces - A candidate substrate for reverse protein arrays in cancer biomarker detection
- Predictive protein signature in the post-polio syndrome: Implications for new diagnosis and treatment
- Reverse-phase versus sandwich antibody microarray, technical comparison from a clinical perspective
- Robotic Implementation of a Protein Profiling Platform Developed for High Throughput Biomarker Discovery
- Study of ATP-release from acoustically levitated eryhrocytes
- Study of ATP-release from acoustically levitated eryhrocytes
- Superhydrophobic Properties of Porous Silicon Improves Surface Based Bioanalysis
- Ultrahydrophobic properties of porous silicon for surface based bioanalysis
- 2006
- 2DDB – a bioinformatics solution for analysis of quantitative proteomics data
- Acoustic Trapping: System Design, Optimization and Applications
- Acoustic separation of particles with similar acoustic properties by means of medium density manipulation
- Fabrication of sample target plate for MALDI-TOF MS using proton beam writing
- High-speed biomarker identification utilizing porous silicon nanovial arrays and MALDI-TOF mass spectrometry
- Hydrolysis of maltoheptaose in flow through silicon wafer microreactors containing immobilised alpha-amylase and glycoamylase
- Improved Carrier Medium Exchange Efficiency in Acoustic Standing Wave Particle Washing
- Miniaturized solid-phase extraction and sample preparation for MALDI MS using a microfabricated integrated selective enrichment target
- Myoelectric control of a computer animated hand: A new concept based on the combined use of a tree-structured artificial neural network and a data glove
- Robotic implementation of a microchip-based protein clean-up and enrichment system for MALDI-TOF MS readout
- Separation of escherichia coli bactreria from raw milk using resonant ultrasound in a microfluidic channel
- Using Acoustic Differential Extraction to enhance analysis of sexual assualt evidence on a valveless glass microdevice
- Whole blood plasmapheresis using acoustic separation chips
- 2005
- A new device for coating single particles under controlled conditions
- Acoustic particle sizing in microchannels by means of ultrasonic frequency switching
- Acoustic trapping of cells in a microfluidic format
- Binary valving of particles using acoustic forces
- Biocompatability of surfaces for antibody microarrays: Design of macroporous silicon substrates
- Biocompatibility of surfaces for antibody microarrays: design of macroporous silicon substrates
- Carrier medium exchange through ultrasonic particle switching in microfluidic channels
- Classification of motor commands using a modified self-organising feature map.
- Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces
- Dynamic arraying of microbeads for bioassays in microfluidic channels
- Flow-through microdispenser for interfacing mu-HPLC to Raman and mid-IR spectroscopic detection
- Improved design and performance of an acoustically operated multi channel particle separation chip
- Influence of Nonuniform Channel Width Distribution in Porous Silicon High Aspect Ratio Parallel Channel Micro Reactors
- Integrated selective enrichment target (ISET) - A generic microfabricated sample preparation device
- Integrating disease knowledge and technology to deliver protein targets and biomarkers into drug discovery projects
- Investigation of micro-immobilised enzyme reactors containing endoglucanases for efficient hydrolysis of cellodextrins and cellulose derivatives
- Lipid microemboli reducion in autotransfusion blood using ultrasonic standing waves in microfluidic channels
- Microchip immobilized enzyme reactors for hydrolysis of methyl cellulose
- Microtechnology Principles and Platforms for Proteomic Analysis
- Miniaturized flowthrough microdispenser with piezoceramic tripod actuation
- Nano-MALDI & Nano-ESI MS, Short specialists review
- Numerical modelling of micro-droplet formation
- Particle separation using ultrasound can be used with human shed mediastinal blood.
- Protein microchip bioassay with dual fluorescent- and MALDI read-out.
- Real-time control of a virtual hand
- Silicon based mu-immobilised enzyme reactors (mu IMER) containing cellulose hydrolysing enzymes
- Temperature evaluation of soft and hard PZT transducers for ultrasonic
- The quest for high-speed and low-volume bioanalysis
- Trapping of microparticles in the near field of an ultrasonic transducer
- Versatile microchip utilising ultrasonic manipulation of microparticles
- Versatile microchip utilising ultrasonic standing waves
- 2004
- Acoustic control of suspended particles in micro fluidic chips
- Array transducer for ultrasonic manipulation of particles
- Autonomous protein sample processing on-chip using solid-phase microextraction, capillary force pumping, and microdispensing
- Bioassays on ultrasonically trapped microbead clusters in microfluidic systems
- Biocampatability of surfaces for antibody microarrays: design of macroporous silicon substrates
- Developments toward a Microfluidic System for Long-Term Monitoring of Dynamic Cellular Events in Immobilized Human Cells.
- In situ poly(ethylene imine) coating of hollow fiber membranes used for microdialysis sampling
- Integrated protein microchip assay with dual fluorescent- and MALDI read-out
- Integrated selective enrichment target - a microtechnology platform for matrix-assisted laser desorption/ionization-mass spectrometry applied on protein biomarkers in prostate diseases
- Micro- and nanotechnology for proteomics
- Microfluidic biosensing systems - Part I. Development and optimisation of enzymatic chemiluminescent mu-biosensors based on silicon microchips
- Microfluidic biosensing systems - Part II. Monitoring the dynamic production of glucose and ethanol from microchip-immobilised yeast cells using enzymatic chemiluminescent mu-biosensors
- Miniaturization in analytical and bioanalytical chemistry
- New directions of miniaturization within the biomarker research area
- Particle separation using ultrasound can radically reduce embolic load to brain after cardiac surgery.
- Pore Chip Protein Microarrays for Bioassay Applications
- Protein Microchip Bioassay with Dual Fluorescent- and MALDI Read-out
- Separation of lipids from blood utilizing ultrasonic standing waves in microfluidic channels.
- Silicon based µ-immobilised enzyme reactors (µIMER) containing cellulose hydrolysing enzymes
- Ultrasonic agitation in microchannels
- Ultrasonic beadtrapping for bioassays
- Ultrasonic particle switching in microfluidic channels
- 2003
- Acoustic Streaming - Ultrasonic Agitation in Microchannels
- Autologous blood recovery and wash in micro fluidic channels utilizing ultrasonic standing waves
- Integrated Protein Microchip Assay with Dual Fluorescent – and MALDI Read-out
- Interfacing mTAS to matrix assisted laser desorption time-of-fight masspectrometry - MALDI-TOF MS
- Macro-/nanoporous Silicon Matrices for Life Science Applications
- Macro-/nanoporous silicon as a support for high-performance protein microarrays
- Macro/nanoporous matrixes for Life Science Applications
- Microfluidic enzyme immunosensors with immobilised protein A and G using chemiluminescence detection
- Microstructure and in silico development for high sensitivity proteomics research
- New directions of miniaturization within the proteomics research area
- On-line monitoring of airborne chemistry in levitated nanodroplets: In situ synthesis and application of SERS-active Ag-sols for trace analysis by FT-Raman spectroscopy
- Particle flow switch using ultrasonic particle switching in microfluidic channels
- Porous Silicon as Substrate for High Sensitivity Protein Chips
- Probe and surface design for antibody microarrays
- Screening of nucleation conditions using levitated drops for protein crystallization
- The beauty of silicon micromachined microstructures interfaced to MALFI-TOF mass spectrometry
- Ultrasonic trapping of microparticles
- 2002
- A microfluidic system for separating fat from blood
- Airborne Single Cell Chemistry
- Autologous blood recovery and wash in microfluidic channel arrays utilizing ultrasonic standing waves
- Biocatalytic porous silicon microreactors
- Design, viualisation and utilisation of enzyme microstructures built on solid surfaces
- Electrochemical etch-stop technique for silicon membranes with p- and n-type regions and its application to neural sieve electrodes
- Flow-through picoliter dispenser: A new approach for solvent elimination in FT-IR spectroscopy
- Highly sensitive microfluidic enzyme immunoassay based on immobilised affinity proteins and chemiluminescence detection
- Homogeneous Porous Layers in High Aspect Ratio Enzyme Microreactors improves performance
- Improved chip design for integrated solid-phase microextraction in on-line proteomic sample preparation
- Improved performance in silicon enzyme microreactors obtained by homogeneous porous silicon carrier matrix
- Macro/Nanoporous silicon as Substrate for Protein Chip Applications
- Manipulation os suspended particles in a laminar flow
- Microfluidic enzyme immunoassay using silicon microchip with immobilized antibodies and chemiluminescence detection
- Microtechnology developments for proteomics research
- Miniaturisation is mandatory unravelling the human proteome.
- Monitoring of human chemiluminescent reporter cell lines expressing G-protein-coupled receptors in a microfluidic system
- Nanostructured high surface area supports for high sensitivity protein chips
- On-chip microextraction for proteomic sample preparation of in-gel digests
- Ready-made matrix-assisted laser desorption/ionization target plates coated with thin matrix layer for automated sample deposition in high-density array format.
- Single framework antibody fragments - designed for protein chip applications
- Tele-Operation of Multi-Finger Virtual/Robot Hand Using Self-Organizing Tree Structured Network on EMG
- Tissue reactions evoked by porous and plane surfaces made out of silicon and titanium.
- 2001
- A method for the design and study of enzyme microstructures formed by means of a flow-through microdispenser
- A miniaturised electrochemical affinity assay based on a wall-free sample droplet and micro-dispensing of the redox-labelled binding partner
- Analysis of regulatory phosphorylation sites in ZAP-70 by capillary high-performance liquid chromatography coupled to electrospray ionization or matrix-assisted laser desorption ionization time-of-flight mass spectrometry
- Determination of diffusion coefficients of electroactive species in time-of-flight experiments using a microdispenser and microelectrodes
- Development of silicon microstructures and thin-film MALDI target plates for automated proteomics sample identifications
- Disposable polymeric high-density nanovial arrays for matrix assisted laser desorption/ionization-time of flight-mass spectrometry: I. Microstructure development and manufacturing
- Disposable polymeric high-density nanovial arrays for matrix assisted laser desorption/ionization-time of flight-mass spectrometry: II. Biological applications
- Downsizing proteolytic digestion and analysis using dispenser-aided sample handling and nanovial matrix-assisted laser/desorption ionization-target arrays.
- Evaluation of glucose biosensors based on Prussian Blue and lyophilised, crystalline and cross-linked glucose oxidases (CLEC(R)).
- Interference elimination in glutamate monitoring with chip integrated enzyme microreactors
- Microdialysis clean-up and sampling in enzyme-based methods for the characterisation of starch
- Microdialysis sampling - Challenges and new frontiers
- Microfluidic components for protein characterization.
- Picodroplet-deposition of enzymes on functionalized self-assembled monolayers as a basis for miniaturized multi-sensor structures
- Protein chips based on recombinant antibody fragments: A highly sensitive approach as detected by mass spectrometry
- Proteomics-protein profiling technology: the trend towards a microfabricated toolbox concept
- Signal amplification using "spot on-a-chip" technology for the identification of proteins via MALDI-TOF MS
- Silicon microstructures for high-speed and high-sensitivity protein identifications
- The geoemtric design of micromachined silicon sieve electrodes influences functional nerve regeneration
- 2000
- 1997
redaktör
- 2009
- An analytical platform for clinical blood sample studies
- Blood plasma peptide profiling by equalizing and multiplex complementary SPE using the microfluidic ISET platform
- Compound tissue imaging signal output generated by different matrix deposition platforms
- Isotope labeled internal standards (ILIS) as the basis for QC-Control in human plasma analysis
- Multiple sclerosis: identification and clinical evaluation of Novel CSF biomarkers for diagnosis and monitoring of disease progression and therapeutic effect
- Multiplex approach for identification of PSA variants in clinical samples
- The Signal Intensity in Imaging MALDI-MS Is Dependent on Matrix Deposition
- 2005
- 2004
