Ingmar Lundquist

författare

• 2012
  • Pancreatic β-cell dysfunction, expression of iNOS and the effect of phosphodiesterase inhibitors in human pancreatic islets of type 2 diabetes.
• 2011
  • Abnormally decreased NO and augmented CO production in islets of the leptin-deficient ob/ob mouse might contribute to explain hyperinsulinemia and islet survival in leptin-resistant type 2 obese diabetes.
  • Insulinotropic and Antidiabetic Effects of 17{beta}-Estradiol and the GPR30 Agonist G-1 on Human Pancreatic Islets.
• 2010
  • ADP mediates inhibition of insulin secretion by activation of P2Y13 receptors in mice.
  • Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice.
  • Defective secretion of islet hormones in chromogranin-B deficient mice.
  • Novel aspects of female sex hormone estrogen in diabetes
• 2009
  • Deletion of the G protein-coupled Receptor GPR30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-stimulated Insulin Release in Female Mice.
  • Imidazoline-induced amplification of glucose- and carbachol-stimulated insulin release includes a marked suppression of islet NO generation in the mouse.
  • Impaired insulin exocytosis in NCAM-/- mice due to defective reorganization of the submembrane F-actin network.
  • Palmitate-stimulated hormone secretion in relation to GPR40 expression in pancreatic islets of spontaneous obesity and type 2 diabetes in rats
  • Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3.
  • The orphan receptor GPR30 and pancreatic islet hormone secretion
• 2008
  • CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic beta Cells.
  • Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1
  • Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.
  • Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.
  • Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.
  • Proghrelin-derived peptides influence the secretion of insulin, glucagon, pancreatic polypeptide and somatostatin: A study on isolated islets from mouse and rat pancreas.
  • Rosiglitazone counteracts palmitate-induced beta-cell dysfunction by suppression of MAP kinase, inducible nitric oxide synthase and caspase 3 activities.
• 2007
  • A(1) receptor deficiency causes increased insulin and glucagon secretion in mice
  • Expression of islet iNOS and inhibition of glucose stimulated insulin release after long-term lipid infusion in the rat is counteracted by PACAP27.
  • Insulin release and islet nitric oxide synthase (NOS) activities in type 2 diabetes obese model, the ob/ob mouse. Interection with regulatory peptides and islet carbon monoxide (CO) production
  • Secretory and electrophysiological characteristics of insulin cells from gastrectomized mice: Evidence for the existence of insulinotropic agents in the stomach.
• 2006
  • Does Epidermal Growth Factor Participate in the Regulation of Glucose, Insulin and Glucagon Levels?
  • Nitric oxide inhibits, and carbon monoxide activates, islet acid {alpha}-glucoside hydrolase activities in parallel with glucose-stimulated insulin secretion.
• 2005
  • A diet based on wheat bread baked with lactic acid improves glucose tolerance in hyperinsulinaemic Zucker (fa/fa) rats
  • CaV2.3 calcium channels control second-phase insulin release.
  • Defective glucose-stimulated insulin release in the diabetic Goto-Kakizaki (GK) rat coincides with reduced activity of the islet carbon monoxide signaling pathway
  • Ghrelin activates neuronal constitutive nitric oxide synthase in pancreatic islet cells while inhibiting insulin release and stimulating glucagon release.
  • Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway
  • Long-term infusion of nutrients (total parenteral nutrition) suppresses circulating ghrelin in food-deprived rats.
• 2004
  • Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.
  • Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.
  • Insulin feedback actions: complex effects involving isoforms of islet nitric oxide synthase.
• 2003
  • A novel mass spectrometric approach to the analysis of hormonal peptides in extracts of mouse pancreatic islets.
  • Carbon monoxide stimulates insulin release and propagates Ca2+ signals between pancreatic beta-cells
  • Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(V)1.2 Ca(2+) channel null mice.
  • Improvement of the metabolic features of bread by use of organic acids
  • Improvement of the metabolic features of bread by use of organic acids
  • Improvement of the metabolic features of bread by use of organic acids
  • Improvement of the metabolic features of bread by use of organic acids
  • Improvement of the metabolic features of bread by use of organic acids.
  • SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells.
  • Total Parenteral Nutrition-Stimulated Activity of Inducible Nitric Oxide Synthase in Rat Pancreatic Islets is Suppressed by Glucagon-Like Peptide-1.
• 2002
  • Förbättring av brödprodukters metabola egenskaper med organiska syror
  • Role of nitric oxide synthase isoforms in glucose-stimulated insulin release.
• 2001
  • TPN-evoked dysfunction of islet lysosomal activity mediates impairment of glucose-stimulated insulin release
  • Total parenteral nutrition modulates hormone release by stimulating expression and activity of inducible nitric oxide synthase in rat pancreatic islets
• 2000
  • Effects of intraluminal trypsin and bile on the exocrine and endocrine pancreas after pancreaticobiliary diversion and biliodigestive shunt
  • Nitric oxide, islet acid glucan-1,4-alpha-glucosidase activity and nutrient-stimulated insulin secretion
• 1999
  • Dysfunction of the islet lysosomal system conveys impairment of glucose-induced insulin release in the diabetic GK rat
  • Gastrectomy induces impaired insulin and glucagon secretion: evidence for a gastro-insular axis in mice
  • Islet constitutive nitric oxide synthase and glucose regulation of insulin release in mice
• 1998
  • Biochemical and ultra-structural reactions to parenteral nutrition with two different fat emulsions in rats
  • Insulin release transduction mechanism through acid glucan 1,4-alpha-glucosidase activation is Ca2+ regulated
  • Signal transduction in islet hormone release: interaction of nitric oxide with basal and nutrient-induced hormone responses
  • The nitric oxide synthase inhibitor NG-nitro-L-arginine methyl ester potentiates insulin secretion stimulated by glucose and L-arginine independently of its action on ATP-sensitive K+ channels
• 1997
  • Total parenteral nutrition influences both endocrine and exocrine function of rat pancreas
• 1996
  • Interaction of the islet nitric oxide system with L-arginine-induced secretion of insulin and glucagon in mice
  • Islet acid glucan-1,4-alpha-glucosidase: a putative key enzyme in nutrient-stimulated insulin secretion
  • Islet constitutive nitric oxide synthase: biochemical determination and regulatory function
  • Modulation of islet G-proteins, alpha-glucosidehydrolase inhibition and insulin release stimulated by various secretagogues
• 1995
  • The pseudotetrasaccharide acarbose inhibits pancreatic islet glucan-1,4-alpha-glucosidase activity in parallel with a suppressive action on glucose-induced insulin release
• 1989
  • Monoamines in pancreatic islets of guinea pig, hamster, rat, and mouse determined by high performance liquid chromatography
• 1981
  • Immunoreactive insulin and C-peptide responses to various insulin secretory stimuli in subjects with type 2 diabetes and in control subjects during continuous glucose monitoring