Carl Persson

författare

• 2013
  • HH Salter (1860s): taking cold as original cause and provocative of attacks of asthma.
• 2012
  • Eotaxins may contribute to both accumulation and elimination of eosinophils in asthma.
  • Increased lung neutrophil apoptosis and inflammation resolution
  • Primary lysis/necrosis of eosinophils and clinical control of asthma.
  • Resolution of leucocyte-mediated mucosal diseases. A novel in vivo paradigm for drug development
  • Selective inhibition by simvastatin of IRF3 phosphorylation and TSLP production in dsRNA-challenged bronchial epithelial cells from COPD donors.
• 2011
  • Exit of leucocytes across the alveolar epithelium worsens lung injury Authors' response
  • Increased fecal leukocytes may reflect resolution of IBD.
  • Letter to Respiratory Medicine: "Drugs reducing transepithelial leukocyte traffic may worsen lung disease"
  • dsRNA-induced expression of thymic stromal lymphopoietin (TSLP) in asthmatic epithelial cells is inhibited by a small airway relaxant.
• 2010
  • Early phase resolution of mucosal eosinophilic inflammation in allergic rhinitis.
  • Resolution of cell-mediated airways diseases
  • Transepithelial exit of leucocytes: inflicting, reflecting or resolving airway inflammation?
• 2009
  • Roles of plasma exudation in asthma and COPD
• 2008
  • Small airway relaxation-A forgotten medical need.
  • Small airways: an important but neglected target in the treatment of obstructive airway diseases
  • Specific nasal symptoms and symptom-provoking factors may predict increased risk of developing COPD.
• 2007
  • Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.
  • Dagens astma- och KOL-terapi har glömt perifer bronkrelaxation. De små luftvägarna spelar en nyckelroll
  • Effects of capsazepine on human small airway responsiveness unravel a novel class of bronchorelaxants.
  • Effects of topical formoterol alone and in combination with budesonide in a pollen season model of allergic rhinitis.
• 2006
  • Effects of steroid treatment on lung CC chemokines, apoptosis and transepithelial cell clearance during development and resolution of allergic airway inflammation.
  • Incidence and remission of self-reported allergic rhinitis symptoms in adults.
  • Obstructive airways diseases, smoking and use of inhaled corticosteroids in southern Sweden in 1992 and 2000.
  • Resolution of airway disease: removal of inflammatory cells through apoptosis, egression or both?
• 2005
  • Alcohol-induced upper airway symptoms: prevalence and co-morbidity.
  • Allergen-exposure of Mouse Airways Evokes Remodeling of both Bronchi and Large Pulmonary Vessels.
  • Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation.
  • Blockade of ctla-4 promotes airway inflammation in naive mice exposed to aerosolized allergen but fails to prevent inhalation tolerance.
  • Challenge-induced plasma exudation and mucinous secretion in human airways
  • Circulating eosinophils in asthma, allergic rhinitis, and atopic dermatitis lack morphological signs of degranulation.
  • Objective monitoring of nasal airway inflammation in rhinitis
  • Secretoneurin is released into human airways by topical histamine but not capsaicin.
• 2004
  • Discontinuous Percoll gradient centrifugation combined with immunomagnetic separation obviates the need for erythrocyte lysis and yields isolated eosinophils with minimal granule abnormalities.
  • Eosinophil degranulation status in allergic rhinitis: observations before and during seasonal allergen exposure.
  • Occurrence of Apoptosis, Secondary Necrosis and Cytolysis in Eosinophilic Nasal Polyps.
  • Rapid and efficient clearance of airway tissue granulocytes through transepithelial migration.
  • Topical treatment with aqueous solutions of rofleponide palmitate and budesonide in a pollen-season model of allergic rhinitis.
• 2003
  • Acute allergic responses induce a prompt luminal entry of airway tissue eosinophils.
  • Airway microvascular extravasation and luminal entry of plasma.
  • Effects of experimental changes in nasal airway pressure on mucosal output of plasma.
  • Effects of loratadine on red wine-induced symptoms and signs of rhinitis.
  • Nasal neutrophil activity and mucinous secretory responsiveness in COPD.
  • Neural expression and increased lavage fluid levels of secretoneurin in seasonal allergic rhinitis.
  • Steroid-sensitive indices of airway inflammation in children with seasonal allergic rhinitis.
• 2002
  • Absorption across the nasal airway mucosa in house dust mite perennial allergic rhinitis.
  • Desloratadine reduces allergen challenge-induced mucinous secretion and plasma exudation in allergic rhinitis.
  • Establishing a model of seasonal allergic rhinitis and demonstrating dose-response to a topical glucocorticosteroid
  • Loss of size-selectivity at histamine-induced exudation of plasma proteins in atopic nasal airways.
  • Mice are not a good model of human airway disease
  • Natural allergen exposure does not diminish the sensitivity of cytokine production to glucocorticosteroids in blood cells of seasonal allergic asthma and rhinitis patients.
  • Prevalence of nasal symptoms and their relation to self-reported asthma and chronic bronchitis/emphysema
• 2001
  • Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammation
  • Lung tissue eosinophils may be cleared through luminal entry rather than apoptosis: effects of steroid treatment
  • Obalanserad medicinsk forskning
  • Unbalanced research
• 2000
  • New aspects of degranulation and fates of airway mucosal eosinophils
  • Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice
• 1999
  • Allergen-induced eosinophil cytolysis is a primary mechanism for granule protein release in human upper airways
  • Degranulation in eosinophils in human, but not in mouse, airways
  • Effects of hydrogen peroxide on the guinea-pig tracheobronchial mucosa in vivo
  • In vivo paradigms of diseased airway mucosa: selected aspects of innate immunity and eosinophils
  • Lack of systemic anaphylaxis and aeroallergen-induced airway plasma extravasation in allergic immunoglobulin-deficient mice
• 1998
  • Contribution of plasma-derived molecules to mucosal immune defence, disease and repair in the airways
  • Generation of clusters of free eosinophil granules (Cfegs) in seasonal allergic rhinitis
  • Plasma-derived proteins in airway defence, disease and repair of epithelial injury
• 1997
  • "Ultimate activation" of eosinophils in vivo: lysis and release of clusters of free eosinophil granules (Cfegs)
  • Airway epithelial repair: breathtakingly quick and multipotentially pathogenic
  • Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice
  • Association between inflammation and epithelial damage-restitution processes in allergic airways in vivo
  • Effects of topical platelet activating factor on the guinea-pig tracheobronchial mucosa in vivo
  • Eosinophil lysis and free granules: an in vivo paradigm for cell activation and drug development
  • Epithelial barrier formation by airway basal cells
  • Epithelium, microcirculation, and eosinophils--new aspects of the allergic airway in vivo
  • Prompt epithelial damage and restitution processes in allergen challenged guinea-pig trachea in vivo
  • The mouse trap
• 1995
  • Airway permeability
  • Effects of topical budesonide on epithelial restitution in vivo in guinea pig trachea
  • Epithelial pathways for luminal entry of bulk plasma
  • In vivo restitution of airway epithelium
  • Topical nitroprusside may reduce histamine-induced plasma exudation in human nasal airways