jalal [dot] taneera [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
- A Central Role for GRB10 in Regulation of Islet Function in Man.
- Downregulation of Type II Diabetes Mellitus and Maturity Onset Diabetes of Young Pathways in Human Pancreatic Islets from Hyperglycemic Donors.
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
- Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia.
- Autoimmunity against INS-IGF2 expressed in human pancreatic islets.
- Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
- Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.
- A common variant upstream of the PAX6 gene influences islet function in man.
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
- Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
- γ-Aminobutyric acid (GABA) signalling in human pancreatic islets is altered in type 2 diabetes.
- A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
- Decreased expression of genes involved in oxidative phosphorylation in human pancreatic islets from patients with type 2 diabetes.
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
- Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets.
- A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
- Bone marrow transplantation stimulates pancreatic β-cell replication after tissue damage.
- Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.
- The impact of differential splicing of TCF7L2 on target gene expression in human islet of Langerhans
- Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.