Distribution of pancreatic polypeptide and peptide YY.
Författare
Summary, in English
The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also found in small numbers in the gastro-intestinal tract. PYY has a dual expression in both endocrine cells and neurons. PYY expressing endocrine cells occur all along the gastrointestinal tract and are frequent in the distal portion. Islet cells expressing PYY are found in many species. In rodents they predominate in the splenic portion (tail) of the pancreas. A limited expression of PYY is found also in endocrine cells in the adrenal gland, respiratory tract and pituitary. Peripheral, particularly enteric, neurons also express PYY as does a restricted set of central neurons.
Publiceringsår
2002
Språk
Engelska
Sidor
251-261
Publikation/Tidskrift/Serie
Peptides
Volym
23
Issue
2
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Cell and Molecular Biology
Nyckelord
- Endocrine Glands/metabolism
- Human
- Microscopy
- Fluorescence
- Neurons/metabolism
- Pancreas/*metabolism
- Pancreatic Polypeptide/*biosynthesis
- Peptide YY/*metabolism
- Respiratory System/metabolism
- Rats
- Animal
- Spleen/metabolism
- Support
- Non-U.S. Gov't
- Adrenal Glands/metabolism
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1873-5169