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Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

In English

Författare

Summary, in English

Clinical use of allografts of fetal ventral mesencephalic tissue as a treatment to replace dopaminergic neurons in patients with Parkinson's disease was first done more than 20 years ago. Since then, many patients have received transplants, with variable results. During this time, our knowledge of Parkinson's disease has changed and the nature and extent of problems associated with the disorder have been better defined. Our understanding on how best to implement this cell-replacement strategy for patients has grown, but gaining this insight has entailed critical reappraisal of data from transplant trials that have already been undertaken.

Publiceringsår

2013

Språk

Engelska

Sidor

84-91

Publikation/Tidskrift/Serie

Lancet Neurology

Volym

12

Issue

1

Dokumenttyp

Artikel i tidskrift

Förlag

Lancet Publishing Group

Ämne

  • Neurology

Status

Published

Forskningsgrupp

  • Neurobiology

ISBN/ISSN/Övrigt

  • ISSN: 1474-4465