Cytogenetic abnormalities in a hemangiopericytoma of the spleen.
Författare
Summary, in English
To date, only 16 cytogenetically abnormal hemangiopericytomas (HP) have been reported. Despite this low number, some characteristic karyotypic features have already emerged: most HP are near-diploid and breakpoints in 12q13, 12q24, and 19q13 seem to be common, with t(12;19)(q13;q13) being a recurrent translocation. Here, we report the first case of a probably benign splenic HP with chromosomal abnormalities. The abnormal karyotype was 47,XX,t(5;22;11)(q31;q11;q13),+10. None of these abnormalities have previously been reported in HP, suggesting that the karyotypic pattern of splenic HP may differ from soft tissue HP.
Publiceringsår
2002
Språk
Engelska
Sidor
62-65
Publikation/Tidskrift/Serie
Cancer Genetics and Cytogenetics
Volym
136
Issue
1
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Surgery
- Medical Genetics
- Cancer and Oncology
Nyckelord
- Male
- Karyotyping
- Immunohistochemistry
- Human
- Hemangiopericytoma : genetics
- Female
- Cytogenetic Analysis
- Case Report
- Chromosome Aberrations
- Splenic Neoplasms : genetics
Status
Published
Forskningsgrupp
- Surgery
ISBN/ISSN/Övrigt
- ISSN: 0165-4608