Chlorhexidine for prevention of neonatal colonization with group B streptococci. III. Effect of vaginal washing with chlorhexidine before rupture of the membranes

Summary, in English

A single vaginal washing with 2 g/l of chlorhexidine was performed before rupture of the membranes in 19 parturients who were urogenital carriers of group B streptococci (GBS). Two (11%) of the infants became colonized immediately after birth, in contrast to 16 of 41 (39%) infants to controls (P = 0.02). A significant reduction of GBS colonization of the ear (P = 0.02) and umbilicus (P = 0.01) was noted. Taken together, 2 of 57 (4%) cultures obtained at birth were positive in the chlorhexidine group, in contrast to 30 of 123 (24%) among the controls (P less than 0.01). These findings raise hope for the design of a simple washing procedure which might prevent serious infections in the early neonatal period with GBS but also with other chlorhexidine-sensitive organisms.

• Författare: K Kvist Christensen; Poul Christensen; Anna-Karin Dykes; Gunnar Kahlmeter
• Avdelning/ar: Institutionen för hälsovetenskaper
• Publiceringsår: 1985
• Språk: Engelska
• Sidor: 231-236
• Publikation/Tidskrift/Serie: European Journal of Obstetrics, Gynecology, and Reproductive Biology
• Volym: 19
• Issue: 4
• Länkar: http://dx.doi.org/10.1016/0028-2243(85)90034-6
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Obstetrics, Gynecology and Reproductive Medicine
• Nyckelord: neonatal colonization; group B streptococci; chlorhexidine
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0301-2115