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Morphological detection of neurogenic muscle disorders: how can statistical methods aid diagnosis?

In English

Författare

Summary, in English

The light microscopical observation of groups of histochemically similar muscle fibres, referred to as fibre-type grouping, is commonly considered to be evidence of a denervation and reinnervation process affecting the spinal motor neurons or the peripheral nerves. It can be difficult to assess whether such groups have occurred by chance or are due to a slowly progressive pathological process in an early stage of development. Consequently, there is a need for one or more objective methods for assessing the fibre-type arrangement in healthy and diseased human muscles. The purposes here are to review the methods for the detection of fibre-type grouping that have been published in the last two decades, to describe some unsolved problems, and to indicate some likely lines of development.

Publiceringsår

1987

Språk

Engelska

Sidor

109-115

Publikation/Tidskrift/Serie

Acta Neuropathologica

Volym

75

Issue

2

Dokumenttyp

Artikel i tidskrift

Förlag

Springer

Ämne

  • Neurosciences

Nyckelord

  • Nerve degeneration
  • Muscular atrophy
  • Muscle denervation
  • Histocytochemistry
  • Aging

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1432-0533