Prenylated isoflavanone from the roots of Erythrina sigmoidea

Summary, in English

A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.

• Författare: Augustin E Nkengfack; Timothee W Vouffo; Z T Fomum; Michele Meyer; Ola Bergendorff; Olov Sterner
• Avdelning/ar: Dermatologi och venereologi, Lund; Centrum för analys och syntes
• Publiceringsår: 1994
• Språk: Engelska
• Sidor: 1047-1051
• Publikation/Tidskrift/Serie: Phytochemistry
• Volym: 36
• Issue: 4
• Länkar: http://dx.doi.org/10.1016/S0031-9422(00)90489-8
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Dermatology and Venereal Diseases
• Nyckelord: Erythrina sigmoidea; Leguminosae; roots; sigmoidin I; neobavaisoflavone; corylin; phaseollidin; antifungal activity
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0031-9422