The Cell Physiology of Biphasic Insulin Secretion
Författare
Summary, in English
Glucose-stimulated insulin secretion consists of a transient first phase followed by a sustained second phase. Diabetes (type II) is associated with abnormalities in this release pattern. Here we review the evidence that biphasic insulin secretion reflects exocytosis of two functional subsets of secretory granules and the implications for diabetes.
Avdelning/ar
Publiceringsår
2000
Språk
Engelska
Sidor
72-77
Publikation/Tidskrift/Serie
News in Physiological Sciences
Volym
15
Issue
2
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
American Physiological Society
Ämne
- Endocrinology and Diabetes
Status
Published
Forskningsgrupp
- Islet cell physiology
- Diabetes - Islet Cell Exocytosis
- Diabetes - Islet Patophysiology
ISBN/ISSN/Övrigt
- ISSN: 1522-161X