Peptidyl diazomethylketones as cysteine protease inhibitors structurally based upon the inhibitory centers of cystatins
Författare
Summary, in English
Six new putative cysteine protease inhibitors based upon sequences of the N-terminal binding fragments of rat cystatin A, bovine cystatin C and human cystatins D and S were synthesized, inhibitory activities of these compounds against papain and bovine cathepsin B were tested. Additionally, agar well diffusion test of their antibacterial activity against Streptococcus pyogenes was performed.
Avdelning/ar
Publiceringsår
2001
Språk
Engelska
Sidor
831-837
Publikation/Tidskrift/Serie
Polish Journal of Chemistry
Volym
75
Issue
6
Dokumenttyp
Artikel i tidskrift
Förlag
Polish Chemical Society
Ämne
- Pharmacology and Toxicology
- Medicinal Chemistry
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0137-5083