Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer.

Summary, in English

As breast volume may be associated with heart cancer risk, we studied the relationship between breast volume, CYP1A2*1F and coffee intake. Among healthy premenopausal non-hormone users, 3+ cups per day was associated with lower volume only in C-allele carriers (P(interaction)=0.02), which is consistent with reports that coffee protects only C-allele carriers against breast cancer.British Journal of Cancer advance online publication, 23 September 2008; doi:10.1038/sj.bjc.6604687 www.bjcancer.com.

• Författare: Helena Jernström; Maria Henningson; Ulla Johansson; Håkan Olsson
• Avdelning/ar: Bröstcancer-genetik
• Publiceringsår: 2008
• Språk: Engelska
• Sidor: 1534-1538
• Publikation/Tidskrift/Serie: British Journal of Cancer
• Volym: 99
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/18813311?dopt=Abstract; http://dx.doi.org/10.1038/sj.bjc.6604687
• Dokumenttyp: Artikel i tidskrift
• Förlag: Nature Publishing Group
• Ämne: Cancer and Oncology
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1532-1827