Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Evaluation of two pairs of chiral stationary phases: Effects from the length of the achiral spacers

Författare

Summary, in English

Two pairs of chiral stationary phases (CSPs) with different C-2-symmetric central parts were prepared and evaluated by chromatography of a series of structurally different racemates. Within each pair, the selectors on which the CSPs are based had different lengths of their achiral spacers. The CSPs based on selectors with short spacers showed higher enantioselectivity than the phases incorporating long spacers. On one pair of the phases, a study of the influence from different retention modifiers was performed for a series of benzodiazepinones. This demonstrated the importance of the polymer structure formed from the selectors with different spacer lengths for the enantiodiscriminating ability of the CSPs. (C) 2004 Wiley-Liss, Inc.

Publiceringsår

2004

Språk

Engelska

Sidor

614-624

Publikation/Tidskrift/Serie

Chirality

Volym

16

Issue

9

Dokumenttyp

Artikel i tidskrift

Förlag

John Wiley & Sons Inc.

Ämne

  • Organic Chemistry

Nyckelord

  • enantioselective liquid chromatography
  • racemate resolution
  • selector
  • synthesis
  • benzodiazepinones
  • multiple hydrogen bonding

Status

Published

Forskningsgrupp

  • Chemical Biology and Therapeutics

ISBN/ISSN/Övrigt

  • ISSN: 1520-636X