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Tobacco smoke as a major source of endotoxin in indoor air

In English

Författare

  • L Larsson
  • Bogumila Szponar
  • Christina Pehrson
  • Aleksandra Sebastian
  • J Rybka

Summary, in English

Mass spectrometry was used to determine the endotoxin (lipopolysaccharide, LPS) marker 3-hydroxytetradecanoic acid and 3-deoxy -D-manno-2-octulosonic acid in cigarette tobacco and smoke particles. Tobacco from cigarettes of different brands purchased in four different countries in Europe and Asia contained similar amounts of LPS. Indoor exposure to environmental tobacco smoke (ETS) in rooms of smoking students entailed inhalation of LPS in amounts that were 6-60 times higher than in student rooms without ongoing smoking. The fact that cigarette smoke contains large amounts of endotoxin may partly explain the high prevalence of respiratory disorders among smokers and may also draw attention to a hitherto unknown or neglected risk factor of ETS.

Publiceringsår

2005

Språk

Engelska

Sidor

1655-1658

Publikation/Tidskrift/Serie

Indoor Air 2005: Proceedings of the 10th International Conference on Indoor Air Quality and Climate, Vols 1-5

Dokumenttyp

Konferensbidrag

Förlag

Tsinghua University Press

Ämne

  • Microbiology in the medical area

Nyckelord

  • Kdo
  • respiratory disorders among smokers
  • acids
  • 3-hydroxy fatty
  • chemical markers
  • indoor air
  • endotoxin
  • tobacco smoke

Conference name

10th International Conference on Indoor Air Quality and Climate (Indoor Air 2005)

Conference date

2005-09-04 - 2005-09-09

Conference place

Beijing, China

Status

Published