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Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.

In English

Författare

Summary, in English

In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.

Publiceringsår

2007

Språk

Engelska

Sidor

808-812

Publikation/Tidskrift/Serie

Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences

Volym

62

Issue

11-12

Dokumenttyp

Artikel i tidskrift

Förlag

Verlag der Zeitschrift für Naturforschung

Ämne

  • Organic Chemistry

Nyckelord

  • limacellone
  • Limacella illinita
  • illinitones
  • 11-desoxyeleganthol

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 0939-5075