New peptaibols from Mycogone cervina

Summary, in English

From cultures of Mycogone cervina, a mycophilic fungus growing on the fruit bodies of ascomycete Paxina acetabulum, two new peptaibols (cervinin, N-Ac-Leu-Aib-Pro-Aib-Leu-Aib-Pro-Ala-Aib-Pro-Val-red-Leu (1) and the red-Leu O-acetylated derivative 2) were isolated. The structures of 1 and 2 were elucidated by spectroscopic techniques. They exhibited weak antibacterial as well as cytotoxic activities. They are the first secondary metabolites described from M. cervina.

• Författare: C Wilhelm; H Anke; Yonny Flores; Olov Sterner
• Avdelning/ar: Centrum för analys och syntes
• Publiceringsår: 2004
• Språk: Engelska
• Sidor: 466-468
• Publikation/Tidskrift/Serie: Journal of Natural Products
• Volym: 67
• Issue: 3
• Länkar: http://dx.doi.org/10.1021/np0302899
• Dokumenttyp: Artikel i tidskrift
• Förlag: The American Chemical Society (ACS)
• Ämne: Organic Chemistry
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0163-3864