Du är här

The Escherichia coli ftsK1 mutation attenuates the induction of sigma(s)-dependent genes upon transition to stationary phase

Författare:
Publiceringsår: 2002
Språk: Engelska
Sidor: 19-23
Publikation/Tidskrift/Serie: FEMS Microbiology Letters
Volym: 206
Nummer: 1
Dokumenttyp: Artikel
Förlag: Elsevier

Sammanfattning

A mutation in the cell division gene ftsK causes super-induction of sigma(70)-dependent stress defense genes, such as uspA, during entry of cells into stationary phase. In contrast, we report here that stationary phase induction of sigma(S)-dependent genes, uspB and cfa, is attenuated and that sigma(S) accumulates at a lower rate in ftsK1 cells. Ectopic overexpression of rpoS restored induction of the rpoS regulon in the ftsK mutant, as did a deletion in the recA gene. Thus, a mutation in the cell division gene,ftsY, uncouples the otherwise coordinated induction of sigma(S)-dependent genes and the universal stress response gene, uspA, during entry into stationary phase. (C) 2002 Federation of European Microbiological Societies, Published by Elsevier Science B.V. All rights reserved.

Disputation

Nyckelord

  • Biology and Life Sciences

Övriga

Published
Yes
  • Microbial Ecology
  • ISSN: 0378-1097

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

LERU logotype U21 logotype

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen