The Central Role of Bcl-3 in Atopic Dermatitis

Summary, in English

Cytokines and hormones are essential mediators in the regulation of antimicrobial peptide and protein (AMP) levels during host defense responses. In this issue, Buchau et al. identify and characterize B-cell leukemia-3 as an important modulator of AMP expression during the innate immune response in keratinocytes as well as in the chronic inflammatory skin disorder atopic dermatitis.

• Författare: Ramin Massoumi
• Avdelning/ar: Cellpatologi, Malmö
• Publiceringsår: 2009
• Språk: Engelska
• Sidor: 2088-2090
• Publikation/Tidskrift/Serie: Journal of Investigative Dermatology
• Volym: 129
• Issue: 9
• Länkar: http://dx.doi.org/10.1038/jid.2009.178
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Dermatology and Venereal Diseases
• Nyckelord: Proto-Oncogene Proteins: physiology; Vitamin D: administration & dosage; Keratinocytes: immunology; Transcription Factors: physiology; Atopic: therapy; Dermatitis; Atopic: immunology; Atopic: etiology; Antimicrobial Cationic Peptides: genetics; Antimicrobial Cationic Peptides: physiology
• Status: Published
• Forskningsgrupp: Cell Pathology, Malmö
• ISBN/ISSN/Övrigt: ISSN: 1523-1747