Spare respiratory capacity, oxidative stress and excitotoxicity
Författare
Summary, in English
Chronic exposure to glutamate (glutamate excitotoxicity) exacerbates neuronal damage in the aftermath of stroke and is implicated in a variety of neurodegenerative disorders. mitochondria play a central role in the survival or death of the exposed neuron. calcium, oxidative stress and ATP insufficiency play closely interlocked roles that may be investigated with primary neuronal cultures.
Publiceringsår
2009
Språk
Engelska
Sidor
1385-1388
Publikation/Tidskrift/Serie
Biochemical Society Transactions
Volym
37
Dokumenttyp
Artikel i tidskrift
Förlag
Biochemical Society
Ämne
- Biochemistry and Molecular Biology
Nyckelord
- oxidative
- mitochondrion
- ischaemia
- glutamate
- ATP
- excitotoxicity
- stress
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0300-5127