Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on Väli et al. (2008).
Författare
Summary, in English
Abstract A recent study by Väli et al. (2008) highlights that microsatellites will often provide a poor prediction of the genome-wide nucleotide diversity of wild populations, but does not fully explain why. To clarify and stress the importance of identity disequilibrium and marker variability for correlations between multilocus heterozygosity and genome-wide genetic variability, we performed a simple simulation with different types of markers, corresponding to microsatellites and SNPs, in populations with different inbreeding history. The importance of identity disequilibrium was apparent for both markers and there was a clear impact of marker variability.
Avdelning/ar
Publiceringsår
2010
Språk
Engelska
Sidor
851-855
Publikation/Tidskrift/Serie
Molecular Ecology
Volym
19
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley-Blackwell
Ämne
- Biological Sciences
Nyckelord
- identity disequilibrium
- genetic diversity
- heterozygosity
- inbreeding
- microsatellites
Status
Published
Forskningsgrupp
- Molecular Ecology and Evolution Lab
ISBN/ISSN/Övrigt
- ISSN: 0962-1083