Du är här

Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on Väli et al. (2008).

Författare:
Publiceringsår: 2010
Språk: Engelska
Sidor: 851-855
Publikation/Tidskrift/Serie: Molecular ecology
Volym: 19
Dokumenttyp: Artikel
Förlag: Blackwell Publishing Ltd

Sammanfattning

Abstract A recent study by Väli et al. (2008) highlights that microsatellites will often provide a poor prediction of the genome-wide nucleotide diversity of wild populations, but does not fully explain why. To clarify and stress the importance of identity disequilibrium and marker variability for correlations between multilocus heterozygosity and genome-wide genetic variability, we performed a simple simulation with different types of markers, corresponding to microsatellites and SNPs, in populations with different inbreeding history. The importance of identity disequilibrium was apparent for both markers and there was a clear impact of marker variability.

Disputation

Nyckelord

  • Biology and Life Sciences
  • identity disequilibrium
  • genetic diversity
  • heterozygosity
  • inbreeding
  • microsatellites

Övriga

Published
  • BECC
Yes
  • Molecular Ecology and Evolution Lab
  • ISSN: 1365-294X

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

 

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen