Aktivt induceret hypotermi efter svaer traumatisk hjerneskade.

Summary, in English

A Cochrane metaanalysis and a study performed on children have recently confirmed that therapeutic hypothermia does not improve outcome after severe traumatic brain injury (TBI). TBI is not comparable to a short episode of global ischemia, where therapeutic hypothermia has been shown to improve outcome. The difference may be explained by the fact that hypothermia-induced stress after a traumatic brain injury reduces cerebral perfusion in the penumbra zone, where local circulation is already reduced. Thus, to date there is no indication for therapeutic hypothermia in TBI patients.

• Författare: Per-Olof Grände; Karen-Lise Welling; Vagn Eskesen; Bertil Romner
• Avdelning/ar: Anestesiologi och intensivvård; Neurokirurgi
• Publiceringsår: 2010
• Språk: Danska
• Sidor: 1437-1440
• Publikation/Tidskrift/Serie: Ugeskrift for Læger
• Volym: 172
• Issue: 19
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/20470652?dopt=Abstract
• Dokumenttyp: Artikel i tidskrift
• Förlag: Den Almindelige Danske Lægeforening
• Ämne: Neurology; Anesthesiology and Intensive Care; Surgery
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0041-5782