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Plasma levels of apolipoprotein M in normal and complicated pregnancy.

Författare

Summary, in English

Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications.

Publiceringsår

2010

Språk

Engelska

Sidor

1214-1217

Publikation/Tidskrift/Serie

Acta Obstetricia et Gynecologica Scandinavica

Volym

89

Issue

9

Dokumenttyp

Artikel i tidskrift

Förlag

Wiley-Blackwell

Ämne

  • Obstetrics, Gynecology and Reproductive Medicine

Nyckelord

  • Pregnancy Complications: blood
  • Pregnancy: blood
  • Apolipoproteins: blood
  • Postpartum Period: blood

Status

Published

Forskningsgrupp

  • Clinical Chemistry, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 1600-0412