Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging
Författare
Summary, in English
Water-dispersible silicon nanoparticles (Si-NPs) are desirable for applications in biological techniques. A simplified method to synthesize such particles is reported here. The resulting Si-NPs are water-dispersible and luminescent. Under the excitation of UV light, the Si-NPs emit strong red light with a peak maximum at 606 nm and a quantum yield of 6%. They are highly stable, and remain so over several weeks. Fourier Transform Infrared (FTIR) spectroscopy shows a visible Si-CH2 scissoring vibration mode. Furthermore, the surface chemical bondings were confirmed by X-ray photoelectron spectroscopy (XPS). In the Si2p and C1s core levels, Si-C components are observed. The diameters of the synthesized Si-NPS as measured by atomic force microscope (AFM) are approximately 5 nm. Furthermore, the nanoparticles can be taken up by cultured cells. Fluorescence images of Si-NPs within MCF-7 human breast cancer cells show they are distributed throughout the cell tissue.
Avdelning/ar
Publiceringsår
2011
Språk
Engelska
Sidor
405-413
Publikation/Tidskrift/Serie
Journal of Nanoparticle Research
Volym
13
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
Springer
Ämne
- Nano Technology
Nyckelord
- Silicon nanoparticles
- Photoluminescence
- X-ray photoelectron
- spectroscopy
- Bio-imaging
- Nanobiology
- Nanomedicine
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1572-896X