Novel supermacroporous dextran gels
Författare
Summary, in English
Supermacroporous dextran gels (SDGs), having pores tens of micrometers in size and highly interconnected, were prepared from dextran macromonomer through radical polymerization at subzero temperatures and compared with dextran gels prepared at ambient temperature. Dextran macromonomer was synthesized via glycidyl methacrylate derivatization of dextran T500 in DMSO medium. The derivatization of dextran was confirmed by H-1-NMR and FT-IR spectroscopy. Scanning electron microscopy revealed macropores up to 100 mu m in size. SDGs can be dried and re-swollen within seconds retaining their porous structure. The large size of interconnected pores, fast swelling and biocompatibility of dextran make SDGs promising material for tissue engineering and cell culture.
Avdelning/ar
Publiceringsår
2006
Språk
Engelska
Sidor
1075-1092
Publikation/Tidskrift/Serie
Journal of Biomaterials Science. Polymer Edition
Volym
17
Issue
10
Dokumenttyp
Artikel i tidskrift
Förlag
VSP BV
Ämne
- Basic Medicine
Nyckelord
- cell
- interconnected pores
- swelling
- dextran
- supermacroporous gel
- scaffolds
Status
Published
Forskningsgrupp
- Insulin Signal Transduction
ISBN/ISSN/Övrigt
- ISSN: 0920-5063