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Monoamine theories of depression: historical impact on biomedical research

In English

Författare

Summary, in English

Monoamine theories associate depression with reduced brain monoamine levels. These theories achieved broad popularity in the mid-1960s. The present article reviews the historical development of monoamine theories and their subsequent impact on biomedical research. Alleged divisions between West European and U.S. researchers over competing versions of the theories are investigated using bibliometrics. Subsequently, the application of monoamine theories in the NIMH Collaborative Program on the Psychobiology of Depression is covered. The paper argues that the impact of monoamine theories is best explained by the ability of researchers, governmental agencies and pharmaceutical companies to invoke theories that advance various projects and agendas.

Publiceringsår

2012

Språk

Engelska

Sidor

366-392

Publikation/Tidskrift/Serie

Journal of the History of the Neurosciences

Volym

21

Issue

4

Dokumenttyp

Artikel i tidskrift

Förlag

Psychology Press

Ämne

  • Gender Studies

Nyckelord

  • depression
  • biological psychiatry
  • history
  • monoamine hypothesis
  • monoamine theory
  • Psychobiology of Depression Program
  • NIMH
  • bibliometrics

Status

Published

Projekt

  • After the success with the new generation antidepressants: Experiences, practices, discourses and changes in the self.

ISBN/ISSN/Övrigt

  • ISSN: 0964-704X