Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Effect of alpha-ketoglutarate given to pregnant sows on the development of the humerus and femur in newborns

In English

Författare

  • E Sliwa
  • S Kowalik
  • MR Tatara
  • W Krupski
  • P Majcher
  • I Luszczewska-Sierakowska
  • Stefan Pierzynowski
  • T Studzinski

Summary, in English

Alpha-ketoglutarate (AKG) was given to pregnant sows every day starting from the 91(st) d of pregnancy to farrowing. At the same time control pregnant sows were treated in the same way with physiological saline (PhS). Newborn piglets from the experimental (AKG) and control (PhS) mothers were euthanised in 1 h after their birth, and the femora and humeri were isolated and frozen at -25 degrees C until further analyses. Using quantitative computed tomography (QCT) method, volumetric bone density of the cortical and trabecular bone compartments were estimated. Moreover, geometrical and mechanical parameters of the bones and the level of osteocalcin and alkaline phosphatase activity in serum were determined. It was found that the administration of AKG to pregnant sows during 24 d before parturition decreased bone density in their newborns.

Publiceringsår

2005

Språk

Engelska

Sidor

117-120

Publikation/Tidskrift/Serie

Bulletin of the Veterinary Institute in Puławy

Volym

49

Issue

1

Dokumenttyp

Artikel i tidskrift

Förlag

National Veterinary Research Institute

Ämne

  • Zoology

Nyckelord

  • alpha-ketoglutarate
  • piglets
  • sow
  • pregnancy
  • bone formation

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 0042-4870