Generation of Transplantable Striatal Projection Neurons from Human ESCs.
Författare
Summary, in English
In this issue of Cell Stem Cell, Ma et al. (2012) report a differentiation protocol for generating striatal projection neurons from human embryonic stem cells with high efficiency. The cells survive transplantation, reconnect striatal circuitry, and restore motor function in a mouse model of striatal neurodegeneration that mimics the central pathohology of Huntington's disease.
Avdelning/ar
Publiceringsår
2012
Språk
Engelska
Sidor
349-350
Publikation/Tidskrift/Serie
Cell Stem Cell
Volym
10
Issue
4
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Cell Press
Ämne
- Cell Biology
Status
Published
Forskningsgrupp
- Neurobiology
- Developmental and Regenerative Neurobiology
ISBN/ISSN/Övrigt
- ISSN: 1934-5909