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Asexuals, Polyploids, Evolutionary Opportunists ...: The Population Genetics of Positive but Deteriorating Mutations.

Publiceringsår: 2012
Språk: Engelska
Sidor: 1393-U499
Publikation/Tidskrift/Serie: Genetics
Volym: 191
Nummer: 4
Dokumenttyp: Artikel
Förlag: Genetics Society of America


Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.



  • Biology and Life Sciences
  • mutation
  • mutational load
  • probability of fixation
  • selecttion


  • Evolutionary Genetics
  • ISSN: 0016-6731 (Print)
  • ISSN: 1943-2631 (Online)

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