Meny

Javascript is not activated in your browser. This website needs javascript activated to work properly.
Du är här

Modelling the evolution of genomes with integrated external and internal functions

Publiceringsår: 2004
Språk: Engelska
Sidor: 271-278
Publikation/Tidskrift/Serie: Journal of Theoretical Biology
Volym: 231
Nummer: 2
Dokumenttyp: Artikel
Förlag: Elsevier

Sammanfattning

The genomes that organisms transmit between generations contain information about different kinds of functions. The genome with the "best" mix and number of genes for these functions is the one that natural selection favours. Here I introduce a new way to model simple organisms with genes for external and internal functions, and use it to study the evolution of genome size. The external functions are exemplified by resource use and the internal functions by mutation control (repair). It is shown that even with a suitable proportion of genes for mutation control, the genomes in the organisms do not forever incorporate genes that increase resource use. Instead they evolve towards an optimal genome of limited size. The optimal proportion of genes for mutation control is shown to have an upper limit given by the ease with which transmission accuracy is improved by adding extra genes for this purpose to the genome. The model illustrates how natural selection on genomes integrates systems for the transmission of genetic information with systems relating to the external adaptation of the organism. It also opens Lip for other, more detailed theoretical investigations of genome functions.

Disputation

Nyckelord

  • Biology and Life Sciences
  • systems
  • gene number
  • mutation repair
  • genome evolution
  • genetic
  • adaptation

Övriga

Published
Yes
  • Evolutionary Genetics
  • ISSN: 0022-5193

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen