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Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis

In English

Författare

Summary, in English

To examine if mild carotid stenosis correlates with silent vascular brain changes, we studied a prospective population-based cohort "Men born in 1914." Data from followups at ages 68 and 81, have been used. Carotid ultrasound was performed at age 81, and cerebral blood flow (CBF) was measured with SPECT at age 82. Out of 123 stroke-free patients, carotid stenosis <50% was observed in 94% in the right and 89% in the left internal carotid arteries (ICAs). In these subjects, Peak Systolic Velocities in ICA correlated negatively with CBF in a majority of several brain areas, especially in mesial temporal area. Results were limited to normotensive until their seventies, who developed late-onset hypertension with a subsequent blood pressure, pulse pressure, and ankle-brachial index growth. Elderly with asymptomatic carotid stenosis <50% and peak systolic velocities in ICA 0.7-1.3 m/s, should be offered an intensified pharmacotherapy to prevent stroke or silent cerebrovascular events.

Publiceringsår

2012

Språk

Engelska

Publikation/Tidskrift/Serie

International Journal of Vascular Medicine

Volym

2012

Dokumenttyp

Artikel i tidskrift

Förlag

Hindawi Limited

Ämne

  • Cardiac and Cardiovascular Systems

Status

Published

Forskningsgrupp

  • Geriatric Medicine
  • Clinical Physiology, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 2090-2824