Subthalamic deep brain stimulation improves smooth pursuit and saccade performance in patients with Parkinson's disease.

Summary, in English

Deep brain stimulation (DBS) in the subthalamic nucleus (STN) significantly reduces symptoms of Parkinson's disease (PD) such as bradykinesia, tremor and rigidity. It also reduces the need for anti-PD medication, and thereby potential side-effects of L-Dopa. Although DBS in the STN is a highly effective therapeutic intervention in PD, its mechanism and effects on oculomotor eye movement control and particularly smooth pursuit eye movements have to date rarely been investigated. Furthermore, previous reports provide conflicting information. The aim was to investigate how DBS in STN affected oculomotor performance in persons with PD using novel analysis techniques.

• Författare: Maria H Nilsson; Mitesh Patel; Stig Rehncrona; Måns Magnusson; Per-Anders Fransson
• Avdelning/ar: Aktivt och hälsosamt åldrande; Öron-, näs- och halssjukdomar, Lund; Neurokirurgi; MultiPark: Multidisciplinary research focused on Parkinson´s disease
• Publiceringsår: 2013
• Språk: Engelska
• Publikation/Tidskrift/Serie: Journal of NeuroEngineering and Rehabilitation
• Volym: 10
• Issue: April,3
• Fulltext: - 347 kB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23551890?dopt=Abstract; http://dx.doi.org/10.1186/1743-0003-10-33
• Dokumenttyp: Artikel i tidskrift
• Förlag: BioMed Central (BMC)
• Ämne: Neurology
• Status: Published
• Forskningsgrupp: Active and Healthy Ageing Research Group
• ISBN/ISSN/Övrigt: ISSN: 1743-0003