Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.
Författare
Summary, in English
Common genetic variations in the gene encoding transcription factor 7-like 2 (TCF7L2) reveal the strongest association with type 2-diabetes known to date. These lead to impaired insulin production and output, but the mechanisms of disease remain incompletely known. In this issue of Diabetologia, two publications provide new insights into TCF7L2-dependent diabetes.
Publiceringsår
2012
Språk
Engelska
Sidor
2559-2561
Publikation/Tidskrift/Serie
Diabetologia
Volym
55
Issue
10
Fulltext
- Available as PDF - 109 kB
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Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Springer
Ämne
- Endocrinology and Diabetes
Status
Published
Forskningsgrupp
- Diabetes - Islet Patophysiology
ISBN/ISSN/Övrigt
- ISSN: 1432-0428