Determination of 14 Circulating microRNAs in Swedes and Iraqis with and without Diabetes Mellitus Type 2.

Summary, in English

Recent reports suggest that immigrants from Middle Eastern countries are a high-risk group for type 2 diabetes (T2D) compared with Swedes, and that the pathogenesis of T2D may be ethnicity-specific. Deregulation of microRNA (miRNA) expression has been demonstrated to be associated with T2D but ethnic differences in miRNA have not been investigated. The aim of this study was to explore the ethnic specific expression (Swedish and Iraqi) of a panel of 14 previously identified miRNAs in patients without T2D (including those with prediabetes) and T2D.

• Författare: Xiao Wang; Jan Sundquist; Bengt Zöller; Ashfaque Memon; Karolina Palmér; Kristina Sundquist; Louise Bennet
• Avdelning/ar: Allmänmedicin och klinisk epidemiologi; Allmänmedicin, kardiovaskulär epidemiologi och levnadsvanor; Allmänmedicin och samhällsmedicin; EpiHealth: Epidemiology for Health
• Publiceringsår: 2014
• Språk: Engelska
• Publikation/Tidskrift/Serie: PLoS ONE
• Volym: 9
• Issue: 1
• Fulltext: - 170 kB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24497980?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0086792
• Dokumenttyp: Artikel i tidskrift
• Förlag: Public Library of Science (PLoS)
• Ämne: Public Health, Global Health, Social Medicine and Epidemiology
• Nyckelord: Aged; Biomarkers; case-control studies; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Iraq; Male; MicroRNAs; Middle Aged; Sweden; Urban Population
• Status: Published
• Projekt: The MEDIM project
• Forskningsgrupp: Family Medicine and Clinical Epidemiology; Family Medicine, Cardiovascular Epidemiology and Lifestyle; Family Medicine and Community Medicine
• ISBN/ISSN/Övrigt: ISSN: 1932-6203