Polymeric micro-channel-based functionalisation system for micro-cantilevers
Författare
Summary, in English
A micro-channel system intended for functionalising micro-cantilevers used for biochemical detection has been designed, realised and characterised. The chip is fabricated in the resist SU-8, which is a photosensitive polymer offering a fast, cost-efficient and easy processing. Cantilevers present a new platform for biochemical detection with a high sensitivity. This micro-channel system is used for treating such a cantilever array with probe molecules prior to detection and it can also be used as the analysis set-up. The design of the micro-channel system provides a simple way of coating separate sections of a cantilever array with different probe molecules. The use of this channel system eliminates the time-consuming step of addressing each cantilever individually to obtain an array functionalised with different probe molecules. Using this micro-channel system in combination with a cantilever array establishes a method of detecting multiple target molecules simultaneously. Fluorescence experiments have been performed to show the working principle of the micro-channel system in combination with a cantilever array.
Publiceringsår
2005
Språk
Engelska
Sidor
281-286
Publikation/Tidskrift/Serie
Ultramicroscopy
Volym
105
Issue
1
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Medical Engineering
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0304-3991