Potential Influence of Diet on Bomb-Pulse Dating of Human Plaque Samples
Författare
Summary, in English
The radiocarbon concentration of different atherosclerotic plaque fragments obtained from 20 patients in Portugal, operated in 2000-2001, has been measured in order to define the year of plaque formation. A difference of 1.8-15 yr was observed, with the mean and median both 9 yr, between the bomb-pulse date estimated with the CALIBomb software and the operation date. Stable isotope (delta C-13 and delta N-15) analysis was also performed and provides insight to the diet of the subjects. The wide range of measured stable isotope values could indicate that the subjects' diet varied, including an abundance of marine foodstuffs. It could also mean a different isotope fractionation process for the different plaque fragments (cap, core, interface to media) and a possible difference in tissues in which the various fragments are formed. Analysis of delta C-13 and delta N-15 values of each patient separately revealed subjects considered more influenced by marine foodstuffs consumption.
Avdelning/ar
- EXODIAB: Excellence of Diabetes Research in Sweden
- EpiHealth: Epidemiology for Health
- MERGE: ModElling the Regional and Global Earth system
- Kärnfysik
- Kardiovaskulär forskning - translationella studier
- Kardiovaskulär forskning - immunitet och ateroskleros
- Avdelningen för Teknisk vattenresurslära
- Kvartärgeologi
- Medicinsk strålningsfysik, Malmö
Publiceringsår
2013
Språk
Engelska
Sidor
874-884
Publikation/Tidskrift/Serie
Radiocarbon
Volym
55
Issue
2-3
Dokumenttyp
Artikel i tidskrift
Förlag
Arizona Board of Regents (University of Arizona)
Ämne
- Cardiac and Cardiovascular Systems
- Radiology, Nuclear Medicine and Medical Imaging
Nyckelord
- bomb-pulse daitng
- human plaque samples
- stable isotopes
Conference name
21st International Radiocarbon Conference, 2012
Conference date
0001-01-02
Status
Published
Forskningsgrupp
- Cardiovascular Research - Translational Studies
- Cardiovascular Research - Immunity and Atherosclerosis
- Medical Radiation Physics, Malmö
ISBN/ISSN/Övrigt
- ISSN: 0033-8222