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How can we determine the molecular clock of malaria parasites?

In English

Författare

Summary, in English

The association of contemporary hosts and their parasites might reflect either cospeciation or more recent shifts among existing hosts. Cospeciation implies that lineages of hosts and parasites diverge in parallel at the same time, but testing this prediction requires time-calibrated phylogenies, which are particularly difficult to obtain in organisms that leave few fossils. It has successively become clear that host shifts have been frequent in the evolutionary history of malaria parasites, but dating these host shifts cannot be done without calibrated phylogenies. Hence, it remains unresolved how long contemporary hosts and vectors have been coevolving with their malaria parasites. This review addresses conflicting rate estimates of molecular evolution and suggests research directions to aid dating diversification events in malaria parasites.

Publiceringsår

2013

Språk

Engelska

Sidor

363-369

Publikation/Tidskrift/Serie

Trends in Parasitology

Volym

29

Issue

8

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Biological Sciences

Nyckelord

  • apicomplexa
  • birds
  • cospeciation
  • host shifts
  • mitochondrial DNA
  • Plasmodium
  • rate calibration

Status

Published

Projekt

  • Malaria in birds

Forskningsgrupp

  • Molecular Ecology and Evolution Lab

ISBN/ISSN/Övrigt

  • ISSN: 1471-5007