Associations between markers of respiratory morbidity in European children
Författare
Summary, in English
School-aged children often experience acute respiratory symptoms. In a multicentre European study, the association between chronic respiratory symptoms (reported in a questionnaire), skin-prick test results, and lung function, and the occurrence of acute respiratory morbidity, was examined among children aged 6-12 yrs with chronic respiratory symptoms. Children with chronic respiratory symptoms, living in 10 European countries, were selected from a parent-completed questionnaire (n=4,307). Atopy was measured with skin-prick tests, and lung function with spirometry. A total of 1,854 (86%, of those in the initial cohort) children kept a successful daily diary regarding their respiratory symptoms for 2-3 months. In multivariate logistic regression analyses, children with asthmatic symptoms, particularly those with doctor-diagnosed asthma, had a greater risk of occurrence of lower respiratory symptoms (odds ratio (OR): 6.12; 95%, confidence interval (CI): 4.99-8.35) than children with a dry nocturnal cough as their only symptom. Atopy, particularly a positive reaction to indoor allergens, was significantly associated with occurrence of lower respiratory symptoms. For atopy the OR was 1.62 (95%, CI: 1.34-1.96). A reduced level of maximal mid-expiratory How was associated with an increased risk of lower respiratory symptoms, cough and phlegm. The associations were similar in Scandinavia, Central Eastern, Western and Southern Europe. To conclude, asthmatic symptoms reported in a questionnaire, atopic status and a reduced level of maximal mid-expiratory flow were associated with the occurrence of acute respiratory symptoms, especially those of lower respiratory symptoms.
Avdelning/ar
Publiceringsår
2002
Språk
Engelska
Sidor
479-486
Publikation/Tidskrift/Serie
European Respiratory Journal
Volym
19
Issue
3
Dokumenttyp
Artikel i tidskrift
Förlag
European Respiratory Society
Ämne
- Respiratory Medicine and Allergy
Nyckelord
- children
- lung function
- atopy
- respiratory symptom
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1399-3003